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Table 3 A description of concordant and discordant classifications for algorithm 12, the algorithm that maximized sensitivity and specificity

From: Validating an algorithm to identify metastatic gastric cancer in the absence of routinely collected TNM staging data

Variable

M1 (n = 1107)

Mnot (n = 1259)

+/+

+/−

−/+

−/−

80%

20%

32%

68%

Age (years)

  < 50

12.5

10.6

7.4

5.8

 50–54

7.6

8.8

5.4

5.1

 55–59

8.9

8.8

9.2

8.5

 60–64

11.1

10.2

8.7

10.6

 65–69

13.2

11.9

13.6

11.8

 70-high

46.8

49.6

55.7

58

Female

35.9

39.4

33.2

34.5

Tumour Location

 Distal

30.4

37.2

37.6

37.7

 Entire

9.9

5.8

9.7

7.7

 GEJ

27.4

30.5

27.2

25.6

 Middle

17

14.2

12.6

16.3

 Proximal

10.6

6.6

8.2

8.5

 Unknown

4.8

5.8

4.7

4.2

Charlson Score

 No Prev Hosp

56.4

49.6

57.9

47.4

 0

29.7

33.2

26.2

29.9

 1

7.6

8.8

7.7

11

 2+

6.2

8.4

12.9

10

Urban Residence

89.2

89.4

87.6

87.7

Community Income

 Lowest

20.2

23

22.5

20

 2

22.9

17.7

23.3

21.6

 3

20

23

18.3

20

 4

20.3

17.7

16.6

20.1

 Highest

16.5

18.6

19.3

17.9

T stage

Tis/T0/T1

1

4.8

2.4

16

T2

1

7.1

3.2

13.8

T3

3.2

20.8

7.7

15.3

T4A

6.2

22.6

15.6

18.9

T4B

27.7

20.8

26.7

11.6

T1-T4A

4

1.8

4.5

3.3

TX

56.9

22.1

39.9

21.2

N status

N0

18.2

25.2

21.3

38.6

N1

3.2

11.1

6.7

14.3

N2

4.1

20.4

8.4

13

N3A

6.2

14.6

9.9

10.8

N3B

3.2

5.8

5.9

4.4

N1–3

50.7

11.1

34.6

7.5

NX

15.3

11.9

13.1

11.5

AJCC Stage

 0/IA

0

2.7

0

11.9

 IB

0

4

0

9.8

 IIA

0

7.5

0

8.9

 IIB

0

8

0

8.2

 IIIA

0

9.7

0

8.5

 IIIB

0

17.7

0

12.2

 IIIC

0

17.7

0

11.6

 IV

100

0

100

0

 Unknown

0

32.3

0

29.2

Death within 1 year

79.7

42.9

55

29.7

Death within 5 years

96.9

74.3

89.6

62.1

  1. +/+ = true positive, +/− false positive, −/+ false negative, −/− true negative