| Italy | Spain | Germany | Australia | Japan | Korea | Taiwan | Brazil | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1LT | 2LT | 1LT | 2LT | 1LT | 2LT | 1LT | 2LT | 1LT | 2LT | 1LT | 2LT | 1LT | 2LT | 1LT | 2LT | |
N = 174 | N = 101 | N = 202 | N = 96 | N = 139 | N = 64 | N = 208 | N = 128 | N = 175 | N = 105 | N = 150 | N = 96 | N = 217 | N = 155 | N = 175 | N = 91 | |
No. imaging tests, n | 155 | 85 | 186 | 72 | 133 | 53 | 191 | 115 | 160 | 97 | 142 | 91 | 192 | 117 | 149 | 72 |
 Mean (SD) | 3.4 (2.6) | 3.0 (3.1) | 4.6 (3.4) | 3.9 (3.3) | 7.0 (4.9) | 5.3 (3.4) | 5.4 (5.0) | 4.7 (4.3) | 16.7 (12.7) | 10.2 (7.8) | 9.3 (8.7) | 10.0 (8.9) | 11.5 (13.4) | 10.6 (14.8) | 3.6 (3.7) | 3.0 (2.4) |
 Median (range) | 3 (1–13) | 2 (1–17) | 4 (1–23) | 3 (1–21) | 6 (1–31) | 5 (1–16) | 4 (1–33) | 3 (1–23) | 14 (1–68) | 8 (1–39) | 7 (1–75) | 8 (1–48) | 8 (1–86) | 5 (1–86) | 3 (1–31) | 2 (1–11) |
Imaging test type, n (%)a | ||||||||||||||||
 Radiograph | 42 (27) | 16 (19) | 77 (41) | 25 (35) | 93 (70) | 30 (57) | 112 (59) | 55 (48) | 147 (92) | 87 (90) | 99 (70) | 68 (75) | 123 (64) | 87 (74) | 16 (11) | 7 (10) |
 PET scan | 45 (29) | 12 (14) | 39 (21) | 5 (7) | 41 (31) | 5 (9) | 56 (29) | 7 (6) | 14 (9) | 4 (4) | 99 (70) | 22 (24) | 42 (22) | 1 (1) | 43 (29) | 6 (8) |
 CT scan | 146 (94) | 78 (92) | 173 (93) | 65 (90) | 127 (96) | 48 (91) | 170 (89) | 109 (95) | 145 (91) | 88 (91) | 131 (92) | 90 (99) | 180 (94) | 86 (74) | 136 (91) | 69 (96) |
 MRI | 28 (18) | 10 (12) | 70 (38) | 21 (29) | 56 (42) | 12 (23) | 32 (17) | 20 (17) | 107 (67) | 58 (60) | 103 (73) | 33 (36) | 72 (38) | 32 (27) | 52 (35) | 15 (21) |
 Ultrasound | 8 (5) | 6 (7) | 18 (10) | 2 (3) | 19 (14) | 2 (4) | 46 (24) | 17 (15) | 19 (12) | 2 (2) | 25 (18) | 5 (6) | 39 (20) | 19 (16) | 8 (5) | 5 (7) |
 Other | 16 (10) | 4 (5) | 32 (17) | 10 (14) | 61 (46) | 9 (17) | 38 (20) | 15 (13) | 92 (58) | 31 (32) | 53 (37) | 29 (32) | 102 (53) | 26 (22) | 48 (32) | 11 (15) |
No. biopsy-related procedure | 129 | 1 | 147 | 3 | 124 | 3 | 146 | 1 | 147 | 0 | 129 | 3 | 168 | 2 | 113 | 1 |
 Mean (SD) | 1.0 (0.2) | 1 (n/a) | 1.1 (0.3) | 1.0 (0) | 1.2 (0.4) | 1.0 (0) | 1.1 (0.3) | 1.0 (n/a) | 1.1 (0.4) | n/a | 1.2 (0.4) | 1.3 (0.6) | 1.1 (0.2) | 1.0 (0) | 1.0 (0.2) | n/a |
 Median (range) | 1 (1–2) | 1 | 1 (1–3) | 1 (1–1) | 1 (1–4) | 1 (1–1) | 1 (1–3) | 1 (1–1) | 1 (1–5) | n/a | 1 (1–2) | 1 (1–2) | 1 (1–2) | 1 (1–1) | 1 (1–2) | 1 (1–1) |
No. biomarker tests | 67 | 6 | 120 | 10 | 67 | 3 | 89 | 16 | 84 | 2 | 102 | 6 | 150 | 3 | 45 | 11 |
 Mean (SD) | 1.2 (0.4) | 1 (0) | 1.5 (0.9) | 1.0 (0) | 2.4 (1.4) | 1.7 (1.2) | 1.5 (0.8) | 1.7 (1.1) | 1.1 (0.4) | 1.0 (0) | 2.2 (0.9) | 1.7 (1.2) | 1.0 (0) | 1.0 (0) | 1.1 (0.3) | 1.2 (0.4) |
 Median (range) | 1 (1–2) | 1 (1–1) | 1 (1–6) | 1 (1–1) | 2 (1–8) | 1 (1–3) | 1 (1–3) | 1 (1–5) | 1 (1–2) | 1 (1–1) | 2 (1–4) | 1 (1–4) | 1 (1–1) | 1 (1–1) | 1 (1–2) | 1 (1–2) |
Test type, number | ||||||||||||||||
 ALK | 17 | 4 | 30 | 1 | 34 | 2 | 16 | 8 | 14 | 1 | 48 | 2 | 0 | 0 | 7 | 4 |
 EGFR | 64 | 2 | 110 | 8 | 62 | 1 | 85 | 10 | 81 | 1 | 96 | 5 | 150 | 3 | 42 | 8 |
 Other | 2 | 0 | 18 | 1 | 47 | 2 | 29 | 7 | 0 | 0 | 80 | 2 | 0 | 0 | 0 | 1 |