Skip to main content

Advertisement

Table 3 Hospitalizations and outpatient visits during first-line and second-line therapy

From: Health care resource use among patients with advanced non-small cell lung cancer: the PIvOTAL retrospective observational study

First-line therapy Italy Spain Germany Australia Japanc Korea Taiwan Brazil
(N = 174) (N = 202) (N = 139) (N = 208) (N = 175) (N = 150) (N = 217) (N = 175)
Admitted to hospital or hospice, n 36 55 61 83 109 83 94 33
 Hospitalization 36 (100) 54 (98) 61 (100) 82 (99) 109 (100) 83 (100) 93 (99) 33 (100)
 Hospice 0 2 (4) 0 6 (7) 0 0 1 (1) 0
Total no. hospitalizationsa 75 112 140 284 242 251 200 42
 No. hospitalizations per patient, median (range) 1 (1–7) 2 (0–7) 2 (1–7) 2 (0–34) 2 (1–10) 2 (1–10) 1 (0–9) 1 (1–3)
Total days of hospitalization per patient, mean (SD) 12.7 (14.1) 17.9 (17.0) 20.6 (29.2) 16.1 (24.4) 42.5 (28.5) 21.3 (29.1) 19.0 (19.3) 21.8 (26.5)
 Median (range) 8 (1–77) 13 (1–100) 9 (1–160) 9 (1–199) 36 (3–146) 12 (1–178) 14 (2–139) 10 (1–90)
LOS per hospitalization (days)b
 Mean (SD) 6.1 (7.8) 8.7 (5.8) 9.0 (11.3) 4.6 (5.7) 19.1 (15.3) 7.1 (9.5) 8.9 (11.2) 17.0 (21.0)
 Median (range) 4 (1–50) 7 (1–28) 4 (1–32) 3 (1–48) 15 (1–81) 3 (1–47) 5 (1–71) 7 (1–77)
No. hospitalizations per 100 pt-wk 1.53 1.81 3.00 4.83 5.49 6.70 2.27 1.03
Total no. emergency visits 6 153 5 73 9 64 125 64
No. emergency visits per 100 pt-wk 0.12 2.47 0.11 1.24 0.20 1.71 1.42 1.57
Patients with OP visits, n 143 119 56 177 117 130 149 94
OP visits, mean (SD) 7.6 (6.9) 9.0 (9.5) 8.7 (9.8) 11.5 (12.7) 14.2 (16.6) 10.6 (10.5) 14.0 (15.3) 7.0 (7.1)
 OP visits, median (range) 5 (1–35) 7 (1–58) 4 (1–41) 7 (1–105) 9 (1–124) 8 (1–58) 10 (1–109) 5 (1–36)
No. OP visits per 100 pt-wk 22.02 17.33 10.43 34.74 37.65 36.94 23.57 16.24
Second-line therapy N = 101 N = 96 N = 64 N = 128 N = 105 N = 96 N = 155 N = 91
Admitted to hospital or hospice, n 9 24 23 37 39 41 62 17
 Hospitalization 9 (100) 24 (100) 23 (100) 36 (97) 39 (100) 40 (98) 62 (100) 17 (100)
 Hospice 0 1 (4) 0 2 (5) 0 2 (5) 0 0
Total no. hospitalizationsa 13 47 39 87 77 78 161 22
 No. hospitalizations per patient, median (range) 1 (1–3) 1 (1–6) 1 (1–5) 1 (0–13) 1 (1–7) 1 (0–8) 2 (1–9) 1 (1–2)
Total days of hospitalization per patient, mean (SD) 10.3 (6.4) 20.1 (23.0) 14.5 (14.5) 13.4 (12.0) 42.3 (26.4) 14.6 (13.1) 20.3 (20.4) 11.6 (9.3)
 Median (range) 9 (3–21) 11 (2–88) 8 (1–49) 10 (2–54) 40 (3–108) 11 (1–56) 13 (2–104) 8 (2–30)
LOS per hospitalization (days)b
 Mean (SD) 7.2 (4.6) 10.5 (5.3) 8.5 (9.5) 5.5 (6.2) 21.7 (15.6) 7.5 (8.5) 7.8 (9.9) 9.0 (7.4)
 Median (range) 8 (1–15) 10 (2–19) 5 (1–32) 4 (1–44) 17 (3–74) 5 (1–56) 4 (1–69) 7 (2–30)
No. hospitalizations per 100 pt-wk 0.60 3.57 2.76 3.63 5.13 3.93 3.47 1.59
Total no. emergency visits 6 52 0 30 6 41 82 25
No. emergency visits per 100 pt-wk 0.28 3.95 0 1.25 0.40 2.07 1.77 1.81
Patients with OP visits, n 72 50 28 96 60 79 90 40
OP visits, mean (SD) 6.9 (7.3) 6.1 (4.2) 5.3 (6.0) 7.3 (6.1) 9.6 (10.0) 9.1 (10.5) 15.4 (17.7) 4.2 (3.9)
 OP visits, median (range) 4 (1–41) 6 (1–17) 3 (1–30) 5 (1–26) 5 (1–49) 5 (1–49) 10 (1–92) 3 (1–18)
No. OP visits per 100 pt-wk 23.00 23.26 10.40 29.08 38.23 36.29 29.79 12.18
  1. aHospitalizations did not include hospice stays
  2. bFor length of stay (LOS), extreme values at the upper end of the distribution were truncated at the 99th percentile of the study population
  3. cSome of the hospitalization, emergency visit, and OP visit data for Japan have been previously reported by Isobe et al. [14]
  4. LOS length of stay in days, No. number of, OP outpatient, pt-wk patient-weeks