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Table 4 Adjusteda Poisson regression models assessing all-cause and breast cancer-specific mortality by surgery pattern for stage I-III breast cancer patients

From: Re-excision and survival following breast conserving surgery in early stage breast cancer patients: a population-based study

  Adjusteda Mortality Rate Ratio (95% CI)
  All-Cause Breast Cancer-Specific
Surgery Pattern P < 0.001 P = 0.07
 BCS 1.00 1.00
 BCS, BCS 0.68 (0.43, 1.09) 1.19 (0.71, 1.97)
 BCS, Mastectomy 0.93 (0.64, 1.36) 1.22 (0.74, 2.00)
 Mastectomy 1.35 (1.15, 1.58) 1.36 (1.08, 1.72)
Geography of Surgery P = 0.11 P = 0.14
 Calgary 1.00 1.00
 Edmonton 1.17 (1.01, 1.37) 1.13 (0.90, 1.42)
 Central 1.16 (0.89, 1.50) 1.10 (0.75, 1.61)
 South 1.29 (1.02, 1.61) 1.39 (1.00, 1.93)
 North 1.33 (0.96, 1.85) 1.62 (1.05, 2.48)
Year of Diagnosis P = 0.024 P = 0.89
 2002 – 2005 1.00 1.00
 2006 – 2009 0.83 (0.71, 0.98) 0.98 (0.78, 1.24)
ER/PR Status & Hormone therapy P < 0.001 P < 0.001
 ER/PR positive & received hormone 1.00 1.00
 ER/PR positive & no hormone 1.51 (1.24, 1.84) 1.25 (0.88, 1.75)
 ER/PR negative 1.96 (1.68, 2.30) 2.61 (2.10, 3.25)
Neo-adjuvant Chemotherapy P = 0.11 P = 0.030
 Not received 1.00 1.00
 Received 0.73 (0.50, 1.06) 0.60 (0.39, 0.94)
Adjuvant Chemotherapy P = 0.002 P = 0.46
 Not received 1.00 1.00
 Received 1.38 (1.12, 1.70) 1.11 (0.84, 1.47)
Tumor Size P < 0.001 P < 0.001
 T0/T1 1.00 1.00
 T2 2.12 (1.82, 2.47) 2.36 (1.85, 3.00)
 T3/T4 2.97 (2.20, 4.01) 4.34 (2.95, 6.36)
Nodal Status P < 0.001 P < 0.001
 N0 1.00 1.00
 N1 1.80 (1.52, 2.13) 2.35 (1.85, 3.00)
 N2/N3 3.00 (2.34, 3.86) 4.53 (3.27, 6.26)
  1. Abbreviations: BCS breast conserving surgery, CI confidence interval, ER estrogen receptor, PR progesterone receptor
  2. aAdjusted for all variables shown in the table, in addition to age during follow-up and time since study start