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Table 5 Association of Indiana’s opioid prescription emergency rules to daily Morphine Equivalent Dose (MED) per patient of opioids dispensed, controlling for potential mediators (n = 1404 days)

From: The effects of state rules on opioid prescribing in Indiana

Daily averages

Impact of policy

Coef. On potential mediator in post policy period

# providers

3.22

−.0010***

# prescriptions per provider

−.28

−.2189**

# days of supply

13.58

−.8037*

MED per day

.24

−.0109

  1. (1)*p ≤ 0.10, **p ≤ 0.05, ***p ≤ 0.01
  2. (2) Includes controls for pre- and post-intervention time trends