The effects of state rules on opioid prescribing in Indiana

Table 1 Association of Indiana’s opioid prescription emergency rules to daily Morphine Equivalent Dose (MED) per patient of opioids dispensed by patient gender, age, payer type, number of scripts within MED per day per patient brackets and by number of days of supply per prescription

	Impact of policy	Pre-policy Time Trend	Post-policy time trend
Gender
Females	−2.80***	−.0027***	−.0042***
Males	−3.68***	−.0014***	−0.0044**
Age
0–20 years	- 27.26***	−.0151***	0.0219***
20–40 years	−3.00***	.0009***	−0.0045***
40–60 years	−2.45***	−.0017***	−0.0023
60+ years	−2.04***	−.0014***	−0.0016
Payer Type
Commercial Ins.	−3.32***	−.0041***	0.0001*
Medicaid	−3.96***	−.0018***	−0.0100***
Medicare	−4.03***	.0037***	−0.0080***
Private Pay	−2.65***	.0007**	−0.0019
Worker’s Comp	−5.93***	.0038***	0.0120*
# scripts within clinically relevant MED per day brackets
0–20	41.72	.4939***	0.1299
20–40	−836.76 ***	−.1699	−0.6885
40–60	−363.90 ***	.2325*	−0.1411
60–80	−126.24***	.0072	−0.2214
80–100	−110.34***	.0511*	0.0058
100+	−345.37***	.1486*	−0.2608
# scripts within clinically relevant # days of supply brackets
0–15	−635.96*	−.3354	−1.2997
16–30	−1077.80***	1.1207***	0.2100
> 30	−49.59***	−.0076	−0.0843**

Coefficients and t-statistics from Interrupted Time Series Analysis. *p ≤ 0.10, **p ≤ 0.05, ***p ≤ 0.01

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