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Table 1 The list of external data used for simulation

From: Construction of a simulation model and evaluation of the effect of potential interventions on the incidence of diabetes and initiation of dialysis due to diabetic nephropathy in Japan

Explanation of variable

Unit

Data source

Period

Example of variable name in the model

Processing (if any)

Calibration or exogenous actual values

Sex- and age category- specific population estimates

Person

Population Estimates

2000–15

pop2029

Not applicable

Calibration

Sex- and age category-specific diabetes prevalence

Person

Meta-regression analysis by Charvat et al. Population Estimates

2000–15

DM2029

Estimated prevalence (%) in 2000, 2005, and 2010 were used to interpolate and extrapolate the estimates during 2000–2015. The percentages were multiplied with sex- and age category-specific population estimates.

Calibration

Sex- and age category-specific number of patients on dialysis due to diabetic nephropathy

Person

An Overview of Regular Dialysis Treatment in Japan

2000–15

DMDi4049

Sex- and age category-specific number was obtained for 2011–15. For 2000–10, the values were estimated using aggregated estimates and age- specific proportion of diabetic nephropathy among all cause in 2011–15.

Calibration

Sex-specific population estimates at the age of 20 (used as inflow toward stocks of age 20–29)

Person/year

Population Estimates

2000–35

Allto20f

The population estimate at the age of less than 20 in 2015 was used to estimate the future population at the age of 20.

Exogenous actual values

Sex-specific population estimates at the age of 40 on dialysis due to diabetic nephropathy (used as inflow toward stock of age 40–49)

Person/year

An Overview of Regular Dialysis Treatment in Japan

2000–15

DMDito40in

Sex-specific numbers in ages 35–39 and 40–44 were averaged and divided by 5.

Exogenous actual values

Sex- and age category-specific mortality rate

1/year

Vital Statistics Population Estimates An Overview of Regular Dialysis Treatment in Japan

2000–15

NDM2029drt, DM2029drt,

DMDi4049drt

The mortality (incidence) was obtained from dividing the number of death by population estimates. The ratio of mortality of non-DM and DM patients were assumed to be 1:2. Actual values for patients on dialysis were used for 2012–2015 and estimated values were used for the rest of the period.

Exogenous actual values