Table 2 Criteria for minimum change in components of metabolic syndrome to assess the primary endpoint
Risk factor for MetS | Clinically significant minimum change | |
|---|---|---|
Men | Women | |
Elevated WC | Reduce by ≥ 5 cm | Reduce by ≥ 6 cm |
Elevated triglycerides | Reduce by ≥ 0.6 mmol/L | Reduce by ≥ 0.5 mmol/L |
Reduced HDL-C | Increase by ≥ 0.15 mmol/L | Increase by ≥ 0.18 mmol/L |
Elevated BP | Reduce by ≥ 7/3 mmHg | Reduce by ≥ 8/4 mmHg |
Elevated HbA1C | Reduce by ≥ 0.4% | Reduce by ≥ 0.5% |