Skip to main content

Table 3 Perceived advantages and drawbacks

From: “No generics, Doctor!” The perspective of general practitioners in two French regions

  N % 95% CI
What do you think are the advantages of generics? (Several possible responses)
 Reduced cost of medicines 258 81.6 78.7–84.3
 Advantages for the health insurance regime 38 12.0 9.9–14.6
 Control of health expenditure 29 9.2 7.2–11.5
 Coherence of prescribing by INNa 18 5.7 4.2–7.6
 Advantages for the patients 6 1.9 1.1–3.2
 Equivalent to the originator 6 1.9 1.1–3.2
 Efficacy equivalent to the originator 5 1.6 0.9–2.8
 Safety equivalent to the originator 0 0 0
 Identical quality to the originator 0 0 0
What do you think are the drawbacks of generics? (Several possible responses)
 Patients may be confused by changes in presentation 148 46.8 43.2–50.5
 Presentation and dosage form differ between laboratories for the same molecule 139 44.0 40.4–47.6
 Patients report more adverse effects 117 37.0 33.6–40.6
 Patients refuse generics 81 25.6 22.6–28.9
 Patients report that generics are less effective 75 23.7 20.8–27.0
 Personal doubt as to equivalence 66 20.9 18.1–24.0
 Poorer treatment compliance by patients 63 19.9 17.2–23.0
 Complexity of prescribing by INN a/name is difficult for the patient 52 16.5 13.9–19.3
 Excipients differ between generics and from the originator 42 13.3 11.0–15.9
 Personal doubts as to efficacy 35 11.1 9.0–13.6
 Doubtful quality 32 10.1 8.1–11.5
 Negative impact on the physician-patient relationship 28 8.9 7.0–11.1
 More frequent allergic manifestations 25 7.9 6.2–10.1
 Personal doubt as to safety of generics 23 7.3 5.6–9.4
 Doubtful manufacturing origin 20 6.3 4.8–8.3
 Complexity of prescribing by INN a/name is difficult for the practitioner 18 5.7 4.2–7.6
 Generics infringe freedom of prescription 13 4.1 2.9–5.8
 Unacceptable demand by the state or health insurance regime 11 3.5 2.4–5.1
 Poor presentation of generics compared with originators 7 2.2 1.4–3.6
  1. aINN, International Non-proprietary Name
\