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Table 1 Demographic and clinical characteristics of all new TB patients who had an unsuccessful TB treatment outcome, stratified by HIV status

From: Unsuccessful TB treatment outcomes with a focus on HIV co-infected cases: a cross-sectional retrospective record review in a high-burdened province of South Africa

Variable TB-HIV Co-infected
n = 9991
n (%)
95% confidence interval) HIV negative
n = 2089
n (%)
95% confidence interval HIV status not recorded
n = 3192
n (%)
95% confidence interval Total
n = 15,272
n (%)
95% confidence interval
Sex
 Male 5276 (52.8) 51.8-53.8 1444 (69.1) 67.1-71.1 1924 (60.3) 58.6-62.0 8644 (56.6) 55.8-57.4
 Female 4715 (47.2) 46.2-48.2 645 (30.9) 28.9-32.6 1268 (39.7) 38.2-41.4 6628 (43.4) 42.6-44.2
Age group
 15-24 816 (8.2) 7.6-8.7 318 (15.2) 13.7-16.8 268 (8.4) 7.4-9.4 1402 (9.2) 8.7-9.6
 25-34 3215 (32.2) 31.3-33.1 342 (16.4) 14.8-17.9 837 (26.2) 24.7-27.7 4394 (28.8) 28.1-29.5
 35-44 3287 (32.9) 32.0-33.8 322 (15.4) 13.9-167.0 805 (25.2) 23.7-26.7 4414 (28.9) 28.2-29.6
 45-54 1903 (19.0) 18.3-19.8 395 (18.9) 17.2-20.6 685 (21.5) 20.0-22.9 2983 (19.5) 18.9-20.2
 55-64 643 (6.4) 5.9-6.9 389 (18.6) 16.9-20.3 362 (11.3) 10.2-21.4 1394 (9.1) 8.7-9.6
 ≥65 127 (1.3)   323 (15.5) 13.9-17.0 235 (7.4) 6.5-8.3 685 (4.5) 4.1-4.8
District
 A 1786 (17.9) 17.1-18.6 3 66 (17.5) 15.9-19.2 448 (14.0) 12.8-15.2 2600 (17.0) 16.4-17.6
 B 2449 (24.5) 23.7-25.4 471 (22.5) 20.8-24.3 482 (15.1) 13.9-16.3 3402 (22.3) 21.6-22.9
 C 2649 (26.5) 25.6-27.4 517 (24.8) 22.8.9-26.6 1007 (31.6) 29.9-33.1 4173 (27.3) 26.728.0
 D 2620 (26.2) 25.4-27.1 540 (25.9) 234.0-27.7 1104 (34.6) 32.9-36.2 4264 (27.9) 27.2-28.6
 E 487 (4.9) 4.4-5.3 195 (9.3) 8.1-10.6 151 (4.7) 4.0-5.5 833 (5.5) 5.1-5.8
Disease classification
 Both 187 (1.9) 1.6-2.1 26 (1.2) 0.7-1.7 42 (1.3) 0.9-1.7 255 (1.7) 1.5-1.9
 Extra-pulmonary 2135 (21.4) 20.6-22.2 307 (14.7) 13.2-16.2 832 (26.1) 24.5-27.6 3274 (21.4) 20.8-22.1
 Pulmonary 7669 (76.7) 75.9-77.6 1756 (84.1) 82.5-85.6 2318 (72.6) 71.0-74.2 11,743 (76.9) 76.2-77.6
Pre-treatment sputum smear resulta
 Sputum smear positive 4346 (61.2) 60.0-62.3 1083 (65.5) 63.2-67.8 1196 (67.4) 65.2-69.6 6625 (62.9) 62.0-63.8
 Sputum smear negative 2760 (38.8) 37.7-40.0 571 (34.5) 32.2-36.8 578 (32.6) 30.3-34.8 3909 (37.1) 36.2-38.0
Treatment delayb
 0-14 days 4772 (83.0) 82.1-84.1 1166 (85.3) 83.4-87.2 1251 (85.5) 83.7-87.3 7189 (83.8) 83.1-84.6
 15+ days 974 (17.0) 16.0-17.9 201 (14.7) 12.8-16.5 212 (14.5) 12.7-16.3 1387 (16.2) 15.4-17.0
On ART/CPT
 Neither on ART nor CPT only 1292 (12.9) 12.3-13.6 NA NA NA NA 1292 (12.9) 12.3-13.6
 On ART only 367 (3.7) 3.3-4.0 NA NA NA NA 367 (3.7) 3.3-4.0
 On CPT only 4202 (42.1) 41.1-43.0 NA NA NA NA 4202 (42.1) 41.1-43.0
 On both ART and CPT 4130 (41.3) 40.4-42.3 NA NA NA NA 4130 (41.3) 40.4-42.3
CD4 count
 1-200 4211 (75.9) 74.7-77.0 NA NA NA NA 4211 (75.9) 74.7-77.0
 201-350 839 (15.1) 14.2-16.1 NA NA NA NA 839 (15.1) 14.2-16.1
 351+ 502 (9.0) 8.2-9.8 NA NA NA NA 502 (9.0) 8.2-9.8
  1. NA not applicable.
  2. aHIV-positive n = 7106, HIV-negative n = 1654, HIV status unknown n = 1774
  3. bHIV-positive n = 5746, HIV-negative n = 1367, HIV status unknown n = 1463