Table 1 Patient demographics and comorbidities by severity of psoriasis

Baseline characteristics in year 2010

Total

Moderate to severe

Mild

p value

(N = 56,406; 100%)

(N = 13,698; 24.3%)

(N = 42,708; 75.7%)

Age (years), mean (SD)

51.63 (14.59)

51.79 (13.95)

51.58 (14.79)

<0.0001

Male, n (%)

28,208 (50.01)

6717 (49.04)

21,491 (50.32)

0.0089

Female (%)

28,198 (49.99)

6981 (50.96)

21,217 (49.68)

 North East

10,485 (18.59)

2478 (18.09)

8007 (18.75)

0.3327

 North Central

16,528 (29.30)

3988 (29.11)

12,540 (29.36)

 South

20,633 (36.58)

5076 (37.06)

15,557 (36.43)

 West

8660 (15.35)

2129 (15.54)

6531 (15.29)

 Missing

100 (0.18)

27 (0.20)

73 (0.17)

 Charlson Comorbidity Index, mean (SD)

0.38 (0.93)

Comorbidities, n (%)

Total

Moderate to severe

Mild

p value

(n = 56,406)

(n = 13,698; 24.3%)

(n = 42,708; 75.7%)

Psoriatic arthritis

5557 (9.85)

2901 (21.18)

2656 (6.22)

<0.0001

Cardiovascular disease

9992 (17.71)

2390 (17.45)

7602 (17.80)

0.3476

Depression

4388 (7.78)

1161 (8.48)

3227 (7.56)

0.0005

Anxiety

3148 (5.58)

734 (5.36)

2414 (5.65)

0.1923

Diabetes

8031 (14.24)

2181 (15.92)

5850 (13.70)

<0.0001

Hyperlipidemia

18,911 (33.53)

4572 (33.38)

14,339 (33.57)

0.6703

Hypertension

19,365 (34.33)

4775 (34.86)

14,590 (34.16)

0.1350

Obesity

2755 (4.88)

709 (5.18)

2046 (4.79)

0.0687

Cerebrovascular disease

2122 (3.76)

462 (3.37)

1660 (3.89)

0.0059

Peripheral vascular disease

2032 (3.60)

457 (3.34)

1575 (3.69)

0.0547

Any of the above comorbidities^a

35,644 (63.19)

9294 (67.85)

26,350 (61.70)

<0.0001