Table 1 Input parameters to model costs and benefits (per CBT participant)
From: Task-shifting alcohol interventions for HIV+ persons in Kenya: a cost-benefit analysis
Parameter | Value | Range | Sources/Reference |
|---|---|---|---|
Benefit 1: Decreased incidence of HIV | $41 | $39 to $43 | |
Efficacy of alcohol intervention: | |||
Percentage of patients reporting abstinence at 90 day follow-up (CBT intervention) | 69% | [54] | |
Percentage of patients reporting abstinence at 90 day follow-up (Usual Care) | 38% | [54] | |
Difference between intervention and usual care in percentage of patients reporting abstinence at 90 day follow-up (parameter 1.1) | 31% | 21% to 41% | |
Percentage of HIV incidence attributable to alcohol consumption (parameter 1.2) | 13% | 1.8 to 16.5% | [86] |
Consumer Price Index/Inflation Rates: | |||
Average 2009 Kenyan CPI | 100 | [60] | |
Average 2010 Kenyan CPI | 106.265 | ||
Average 2011 Kenyan CPI | 121.17 | ||
Average 2013 Kenyan CPI | 140.103 | ||
Costs of treating new case of HIV: | |||
Average non-drug related costs (2009 USD) | |||
Lab tests | 32 | 29.2 to 36.2 | [66] |
Visits | 24 | 18.8 to 29.2 | |
Support services | 0.4 | 0.10 to 0.90 | |
Fixed costs | 32 | 22.4 to 46.6 | |
Sum of mean non-drug related costs (2013 USD) | 124 | [66] | |
Median drug costs in USD: | |||
12 Month tenofovir/3TC/EFV drug regimen (2013 price) | 145.47 | 145.47–280.72 | [68] |
Benefit 2: Increased Productivity | |||
Labor Force Participation: | |||
Average Monthly Min Wages (parameter 2.4 for LFP hours), USD (KES) | 76.93 (6503) | 57.42 to 103.60 (4854 to 8757) | [87] |
Percentage rise in weekly hours worked after ARV treatment (LFP hours for parameter 2.3) | 19% | 3.7% to 34% (Normal Distribution, SE = 1.88, Mean = 4.6, Baseline total hours = 24.3) | [74] |
Household Productivity: | |||
Increase in female hours spent collecting parameter in past week: (HP hours for parameter 2.3) | |||
Firewood | 1.056 | 0.15 to 1.96 (Normal distribution, SE = 0.461) | [78] |
Water | 1.945 | 0.86 to 3.03 (Normal distribution, SE = 0.556) | [78] |
Average Hourly Min Wage for House Worker (parameter 2.4 for HP hours), USD (KES) | 0.85 (72) | 0.58 to 1.03 (49–87) | [87] |
Increase in ARV adherence due to increased abstinence: | |||
Hazardous Drinkers (number of patients non-adherent/exposed) | 27.54% (19/69) | [7] | |
Non-Drinkers (number of patients non-adherent/exposed) | 7.78% (112/1439) | [7] | |
Increase in the likelihood that an HIV+ patient which moves from non-abstinence to abstinence behavior will be ARV-adherent (parameter 2.2) | 19.75% | 14.75% to 24.75% | Calculated from above values |
Currency Exchange (1USD: KES) | 84.53 | [61] | |