Table 8 Sensitivity analysis for odds ratios modeling death, for patients who are adherent versus non-adherent to anti-hypertensive medication, using different thresholds to define adherence
From: Measuring medication adherence in patients with incident hypertension: a retrospective cohort study
Adjusted ORa | 95% CI | P value | |||
|---|---|---|---|---|---|
Adherence >0.65 | MPRi | Low | 0.96 | (0.74, 1.26) | 0.787 |
High | 0.91 | (0.65, 1.26) | 0.560 | ||
Sum | 0.89 | (0.62, 1.27) | 0.509 | ||
Mean | 0.99 | (0.75, 1.31) | 0.940 | ||
MPRp | Low | 0.74 | (0.52, 1.06) | 0.101 | |
High | 0.81 | (0.53, 1.23) | 0.317 | ||
Sum | 0.80 | (0.52, 1.22) | 0.294 | ||
Mean | 0.78 | (0.53, 1.16) | 0.222 | ||
PDC | 0.84 | (0.60, 1.14) | 0.323 | ||
Adherence >0.70 | MPRi | Low | 0.92 | (0.71, 1.19) | 0.514 |
High | 0.87 | (0.64, 1.19) | 0.385 | ||
Sum | 0.78 | (0.56, 1.09) | 0.151 | ||
Mean | 0.88 | (0.67, 1.14) | 0.324 | ||
MPRp | Low | 0.71 | (0.51, 0.98) | 0.036 | |
High | 0.71 | (0.49, 1.02) | 0.063 | ||
Sum | 0.69 | (0.48, 1.00) | 0.052 | ||
Mean | 0.64 | (0.45, 0.90) | 0.011 | ||
PDC | 0.77 | (0.56, 1.07) | 0.117 | ||
Adherence >0.75 | MPRi | Low | 0.96 | (0.75, 1.24) | 0.767 |
High | 0.91 | (0.68, 1.21) | 0.515 | ||
Sum | 0.81 | (0.59, 1.11) | 0.186 | ||
Mean | 0.88 | (0.68, 1.14) | 0.322 | ||
MPRp | Low | 0.74 | (0.55, 1.00) | 0.053 | |
High | 0.77 | (0.54, 1.08) | 0.132 | ||
Sum | 0.71 | (0.50, 1.00) | 0.052 | ||
Mean | 0.70 | (0.51, 0.97) | 0.030 | ||
PDC | 0.82 | (0.61, 1.11) | 0.203 | ||
Adherence >0.80 | MPRi | Low | 0.96 | (0.74, 1.23) | 0.743 |
High | 0.90 | (0.68, 1.19) | 0.475 | ||
Sum | 0.78 | (0.58, 1.05) | 0.104 | ||
Mean | 0.88 | (0.68, 1.13) | 0.321 | ||
MPRp | Low | 0.79 | (0.59, 1.05) | 0.098 | |
High | 0.76 | (0.56, 1.05) | 0.094 | ||
Sum | 0.70 | (0.51, 0.97) | 0.029 | ||
Mean | 0.71 | (0.53, 0.95) | 0.021 | ||
PDC | 0.80 | (0.60, 1.07) | 0.130 | ||
Adherence >0.85 | MPRi | Low | 0.89 | (0.69, 1.15) | 0.367 |
High | 0.83 | (0.64, 1.08) | 0.175 | ||
Sum | 0.75 | (0.57, 0.99) | 0.044 | ||
Mean | 0.88 | (0.69, 1.13) | 0.329 | ||
MPRp | Low | 0.80 | (0.61, 1.05) | 0.103 | |
High | 0.80 | (0.59, 1.07) | 0.136 | ||
Sum | 0.70 | (0.52, 0.94) | 0.018 | ||
Mean | 0.80 | (0.61, 1.06) | 0.120 | ||
PDC | 0.79 | (0.60, 1.04) | 0.095 | ||
Adherence >0.90 | MPRi | Low | 0.95 | (0.74, 1.23) | 0.713 |
High | 0.92 | (0.71, 1.18) | 0.500 | ||
Sum | 0.85 | (0.65, 1.12) | 0.244 | ||
Mean | 0.93 | (0.72, 1.20) | 0.589 | ||
MPRp | Low | 0.83 | (0.64, 1.07) | 0.156 | |
High | 0.89 | (0.68, 1.18) | 0.427 | ||
Sum | 0.79 | (0.59, 1.04) | 0.094 | ||
Mean | 0.86 | (0.66, 1.11) | 0.250 | ||
PDC | 0.88 | (0.67, 1.14) | 0.332 | ||