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Table 6 Adjusted logistic regression modeling the odds ratio of death, for patients who are adherent versus non-adherent to anti-hypertensive medication

From: Measuring medication adherence in patients with incident hypertension: a retrospective cohort study

 

Adjusted ORb

95% CI

P value

Overall

MPRi

Low

0.96

(0.74, 1.23)

0.743

High

0.90

(0.68, 1.19)

0.475

Sum

0.78

(0.58, 1.05)

0.104

Mean

0.88

(0.68, 1.13)

0.321

MPRp

Low

0.79

(0.59, 1.05)

0.098

High

0.76

(0.56, 1.05)

0.094

Sum

0.70

(0.51, 0.97)

0.029

Mean

0.71

(0.53, 0.95)

0.021

PDC

0.80

(0.60, 1.07)

0.130

Monotherapy

MPRi

0.80

(0.40, 1.57)

0.510

MPRp

0.74

(0.33, 1.66)

0.461

PDC

0.80

(0.40, 1.57)

0.510

Polytherapy

MPRi

Low

1.06

(0.64, 1.73)

0.832

High

1.15

(0.71, 1.85)

0.578

Sum

0.74

(0.37, 1.49)

0.400

Mean

0.83

(0.53, 1.31)

0.426

MPRp

Low

0.84

(0.53, 1.33)

0.455

High

0.99

(0.50, 1.97)

0.975

Sum

0.65

(0.31, 1.36)

0.251

Mean

0.66

(0.40, 1.10)

0.112

PDC

0.80

(0.46, 1.38)

0.424

  1. b Adjusted for age, sex, Charlson comorbidity index, income quintile, and previous hospitalization for cardiovascular disease
  2. Where “Low” = adherence estimate for the single medication class with the lowest adherence; “High” = adherence estimate for the single medication class with the highest adherence; “Sum” = adherence to any medication class (where days supply for each medication class summed as the numerator); “Mean” = mean adherence to each medication class
  3. Abbreviations: OR odds ratio, CI confidence interval, MPRi interval based medication possession ratio, MPRp prescription based medication possession ratio, PDC proportion of days covered