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Table 4 Mean and median adherence rates, and proportion with adherence ≥0.80 for patients on monotherapy (n = 1422)

From: Measuring medication adherence in patients with incident hypertension: a retrospective cohort study

  

Range

Mean (SD)

Median (IQR)

Proportion ≥0.80

Overall

MPRi

0.04–1.00

0.83 (0.23)

0.95 (0.75, 0.99)

71.8%

MPRp

0.04–1.00

0.87 (0.19)

0.96 (0.82, 1.00)

76.7%

PDC

0.08–1.00

0.82 (0.23)

0.93 (0.72, 0.99)

67.9%

Age

65 to 74 years

MPRi

0.08–1.00

0.82 (0.23)

0.93 (0.72, 0.99)

67.9%

MPRp

0.09–1.00

0.85 (0.21)

0.95 (0.78, 1.00)

73.6%

PDC

0.08–1.00

0.82 (0.23)

0.93 (0.72, 0.99)

67.9%

75 years and over

MPRi

0.04–1.00

0.84 (0.22)

0.95 (0.77, 0.99)

73.4%

MPRp

0.04–1.00

0.87 (0.19)

0.96 (0.83, 1.00)

77.9%

PDC

0.04–1.00

0.84 (0.22)

0.95 (0.77, 0.99)

73.4%

Sex

Male

MPRi

0.04–1.00

0.82 (0.23)

0.94 (0.73, 0.99)

67.9%

MPRp

0.04–1.00

0.85 (0.21)

0.95 (0.80, 1.00)

73.6%

PDC

0.04–1.00

0.82 (0.23)

0.94 (0.73, 0.99)

67.9%

Female

MPRi

0.10–1.00

0.84 (0.22)

0.96 (0.78, 0.99)

73.4%

MPRp

0.08–1.00

0.87 (0.19)

0.96 (0.82, 1.00)

77.9%

PDC

0.10–1.00

0.84 (0.22)

0.96 (0.78, 0.99)

73.4%

Income

Lowest quintile

MPRi

0.05–1.00

0.83 (0.24)

0.95 (0.77, 0.99)

73.1%

 

MPRp

0.04–1.00

0.87 (0.20)

0.96 (0.83, 1.00)

77.9%

 

PDC

0.05–1.00

0.83 (0.24)

0.95 (0.77, 0.99)

73.1%

Highest quintile

MPRi

0.10–1.00

0.85 (0.20)

0.95 (0.74, 0.99)

71.7%

Charlson

comorbidities

0 or 1 comorbidities

MPRi

0.04–1.00

0.84 (0.22)

0.95 (0.76, 0.99)

72.6%

MPRp

0.08–1.00

0.87 (0.19)

0.96 (0.82, 1.00)

77.2%

PDC

0.04–1.00

0.84 (0.22)

0.95 (0.76, 0.99)

72.6%

2+ comorbidities

MPRi

0.05–1.00

0.79 (0.26)

0.92 (0.61, 1.00)

63.9%

MPRp

0.04–1.00

0.83 (0.23)

0.94 (0.77, 1.00)

71.5%

PDC

0.05–1.00

0.79 (0.26)

0.92 (0.61, 1.00)

63.9%

  1. Abbreviations: SD standard deviation, IQR interquartile range, MPRi interval based medication possession ratio, MPRp prescription based medication possession ratio, PDC proportion of days covered