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Table 1 Summary of parameters used for depression progression, screening and case-finding

From: The cost-effectiveness of changes to the care pathway used to identify depression and provide treatment amongst people with diabetes in England: a model-based economic evaluation

Parameters

Value

Source

Incidence of depression (per year) in patients with diabetes and no history of depression

 Minor

5.4%

Assumption

 Major

5.4%

Nefs et al. [20]

Time to progression (years)

 Minor to major depression

42% at 2 years

Bot et al. [19]

Time to relapse of depression for patients with a history of depression (years)

 Minor

1.359

Assumption

 Major

1.359

Lutsman et al. [21]

Time to spontaneous recovery (years)

 Minor

0.354

NICE CG90 [24]

 Major

0.877

Spijker et al. (2002) [38]

Average annual number of GP appointments (other than appointments associated with depression treatment)

  

 • cigDiabetes, no depression

 • Diabetes with minor depression

 • Diabetes with major depression

12.5

8

8

Bhattarai et al. [22]

Assumption

Assumption

Probability that a GP appointment includes a depression screen

  

 • No history of depression

 • History of depression

5%

20%

Assumption

Probability of attending annual diabetes review

 

QOF 2012/13 [39] DM29

 • No depression

 • Minor depression

 • Major depression

90.4%

RRa: 0.9

RRa: 0.65

Assumption

Assumption

Probability that the annual review includes a depression screen

85.9%

QOF 2012/13 [39] DEP1

Effectiveness of screening

  

 • Sensitivity of Whooley questions

 • Specificity of Whooley questions

 • Sensitivity of structured interview

 • Specificity of structured interview

95%

66%

100%

100%

NICE CG91 [11]

NICE CG91 [11]

Assumption

Assumption

  1. a RR Relative risk. Values are relative to no depression, with values <1 indicating that patients are less likely to attend the annual diabetes review. QOF Quality and outcomes framework