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Table 1 Summary of parameters used for depression progression, screening and case-finding

From: The cost-effectiveness of changes to the care pathway used to identify depression and provide treatment amongst people with diabetes in England: a model-based economic evaluation

Parameters Value Source
Incidence of depression (per year) in patients with diabetes and no history of depression
 Minor 5.4% Assumption
 Major 5.4% Nefs et al. [20]
Time to progression (years)
 Minor to major depression 42% at 2 years Bot et al. [19]
Time to relapse of depression for patients with a history of depression (years)
 Minor 1.359 Assumption
 Major 1.359 Lutsman et al. [21]
Time to spontaneous recovery (years)
 Minor 0.354 NICE CG90 [24]
 Major 0.877 Spijker et al. (2002) [38]
Average annual number of GP appointments (other than appointments associated with depression treatment)   
 • cigDiabetes, no depression
 • Diabetes with minor depression
 • Diabetes with major depression
12.5
8
8
Bhattarai et al. [22]
Assumption
Assumption
Probability that a GP appointment includes a depression screen   
 • No history of depression
 • History of depression
5%
20%
Assumption
Probability of attending annual diabetes review   QOF 2012/13 [39] DM29
 • No depression
 • Minor depression
 • Major depression
90.4%
RRa: 0.9
RRa: 0.65
Assumption
Assumption
Probability that the annual review includes a depression screen 85.9% QOF 2012/13 [39] DEP1
Effectiveness of screening   
 • Sensitivity of Whooley questions
 • Specificity of Whooley questions
 • Sensitivity of structured interview
 • Specificity of structured interview
95%
66%
100%
100%
NICE CG91 [11]
NICE CG91 [11]
Assumption
Assumption
  1. a RR Relative risk. Values are relative to no depression, with values <1 indicating that patients are less likely to attend the annual diabetes review. QOF Quality and outcomes framework