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Table 5 Comparison between the WHO PMWC list and SA STG/EMLs

From: Quantitative evaluation of essential medicines lists: the South African case study

Priority life‐saving medicines for children under five years of age for major causes of mortality and morbidity, palliative care and child survival
Condition Drug Formulation and Strength PHC 2008 ADULT 2012 PAED 2013
Mol DF Mol DF Mol DF
Pneumonia Amoxicillin dispersible, scored tablets 250 mg and 500 mg or equivalent flexible oral solid dosage form X    X
Pneumonia Ampicillin powder for injection 500 mg and 1 g X     IV
Pneumonia Ceftriaxone powder for injection 250 mg and 1 g IV    IV
Pneumonia Gentamicin injection 40 mg/ml; 20 mg/ml X     IV
Pneumonia Oxygen medicinal gas     
Diarrhoea Oral rehydration salts (ORS): sachets of 200 ml; 500 ml and 1 l, appropriate flavour sachets    sachets
Diarrhoea Zinc 20 mg scored dispersible tablet or equivalent flexible oral solid dosage form X     X  
Malaria Artemesinin combination therapy (ACT) dispersible tablet or flexible oral solid dosage form and dose optimized X     X  
Malaria Artesunate rectal and injection dosage forms 50–200 mg X     X  
Neonatal sepsis Ampicillin powder fir injection 250 mg and 500 mg X     IV
Neonatal sepsis Ceftriaxone powder for injection 250 mg and 500 mg IV    IV
Neonatal sepsis Gentamicin injection 40 mg/ml; 20 mg/ml X     IV
Neonatal sepsis Procaine benzylpenicillin powder for injection 1 g X     IM
HIV Standard regimen for first-line antiretroviral treatment 1 NNRTI + 2 NRTIs e.g. lamivudine + nevirapine + zidovudine - tablet 30 mg + 50 mg + 60 mg; 150 mg + 200 mg + 300 mg oral    oral
Vitamin A deficiency Vitamin A capsule 100 000 IU strength; 200 000 IU strength capsule    capsule
Palliative care/Pain Morphine granules 20 mg, 30 mg, 60 mg, 100 mg, 200 mg; injection 10 mg/ml, oral liquid 10 mg/5 ml, IV    Oral liquid
Palliative care/Pain Paracetamol variable flexible oral solid dosage forms x    x
Vaccines BCG      
Vaccines Hepatitis B      
Vaccines Polio      
Vaccines DTP      X  
Vaccines Haemophilus influenze Type b      X  
Vaccines Pneumococcal (conjugate)   X     
Vaccines Rotavirus   X     X  
Vaccines Measles      
Vaccines Rubella   X     X  
Vaccines HPV   X     X  
Vaccines Japanese Encephalitis   X     X  
Vaccines Yellow fever   X     X  
Vaccines Tick Borne encephalitis   X     X  
Vaccines Typhoid   X     X  
Vaccines Cholera   X     X  
Vaccines Meningococcal   X     X  
Vaccines Hepatitis A   X     X  
Vaccines Rabies      
Vaccines Mumps   X     X  
Vaccines Influenze (Inactivated)      
Priority life‐saving medicines for women for major causes of sexual and reproductive health related mortality and morbidity  
 Post-partum haemorrhage Oxytocin injection 10 IU in 1‐ml ampoule     
 Post-partum haemorrhage Misoprostol tablet 200 micrograms (when oxytocin is not available or cannot safely be used)     
 Post-partum haemorrhage Sodium chloride injectable solution 0.9% isotonic or     
 Post-partum haemorrhage Sodium lactate compound injectable solution (Ringer’s lactate) for infusion   X    
 Severe pre‐eclampsia/eclampsia Magnesium sulfate injection 500 mg/ml in 10‐ml ampoule     
 Severe pre‐eclampsia/eclampsia Calcium gluconate injection (for treatment of magnesium toxicity) 100 mg/ml in 10‐ml ampoule     
 Severe pre‐eclampsia/eclampsia Hydralazine powder for injection 20 mg (hydrochloride) in ampoule or tablet 25 mg; 50 mg (hydrochloride) X     
 Severe pre‐eclampsia/eclampsia Methyldopa tablet 250 mg     
 Maternal sepsis Ampicillin powder for injection 500 mg; 1 g X     
 Maternal sepsis Gentamicin injection 40 mg/ml in 2‐ml vial X     
 Maternal sepsis Metronidazole injection 500 mg in 100‐ml vial X     
 Abortion/miscarriage Misoprostol tablet 200 micrograms     
 Abortion/miscarriage Mifepristone + misoprostol tablet 200 mg + tablet 200 micrograms (where permitted under national law) X     
 STIs Azithromycin capsule 250 mg; 500 mg or oral liquid 200 mg/5 ml X   X    
 STIs Cefixime capsule 400 mg     
 STIs Benzathine Benzylpenicillin powder for injection 900 mg benzylpenicillin in 5 ml vial; 1,44 g benzylpenicillin in 5 ml vial     
 Preterm labour Nifedipine immediate release capsule 10 mg     
 preterm labour (foetal lung maturity) Dexamethasone injection 4 mg dexamethasone phosphate (as disodium salt) in 1‐ml ampoule or X     
 preterm labour (foetal lung maturity) Betamethasone injection 6 mg/ml (3 mg/ml betamethasone sodium phosphate + 3 mg/ml betamethasone acetate) in an aqueous vehicle     
 Maternal Malaria Artesunate parenteral X   X    
 Maternal Malaria Artemether parenteral X   X    
 Maternal Malaria Quinine parenteral     
 Maternal HIV/AIDS AZT; 3TC; EFV; NVP; EFV; TDF; FTC; ABC; LPV Doses not stipulated     
 Prevention of tetanus from MTC Tetanus vaccine      
 Contraception Oral contraceptives such as ethinylestradiol + levonorgestrel tablet 30 micrograms + 150 micrograms;     
 Contraception levonorgestrel 750 micrograms (pack of 2);   X    
 Contraception Injectable: estradiol cypionate + medroxyprogesterone acetate injection 5 mg + 25 mg or X   X    
 Contraception medroxyprogesterone acetate depot injection 150 mg/ml in 1‐ml vial or   X    
 Contraception norethisterone enantate 200 mg/ml in 1‐ml ampoule   X    
 Contraception implantable: levonorgestrel-releasing implant 150 mg total X   X    
 Contraception intrauterine devices and barrier methods of contraception copper-containing devices; condoms; diaphragms   X    
  1. Mol Molecule, DF Dosage Form