| Estonia | Russia | South Africa | Peru | China | Philippines | India |
---|---|---|---|---|---|---|---|
Cohort | |||||||
 Populationa, cases (n) | 38 | 6,537 | 6,494 | 564 | 826 | 11 | 20,763 |
Estimated Total DALYs, avoided | |||||||
 Bedaquiline + BR | 438.41 | 72,824.26 | 78,816.95 | 8,318.51 | 7,329.94 | 152.50 | 299,598.12 |
 BR only | 554.29 | 90,479.07 | 96,530.04 | 10,475.26 | 9,792.45 | 177.64 | 384,990.40 |
Estimated DALYs per patient, avoided | |||||||
 Bedaquiline + BR | 11.54 | 11.14 | 12.14 | 14.75 | 8.87 | 13.86 | 14.43 |
 BR only | 14.59 | 13.84 | 14.86 | 18.57 | 11.86 | 16.15 | 18.54 |
 Incremental change in DALYs (bedaquiline + BR vs. BR) (%, relative to bedaquiline) | -20.90 | -19.51 | -18.35 | -20.59 | -25.15 | -14.16 | -22.18 |
Patients with successful outcomes (%) | |||||||
 Bedaquiline + BR | 40.66 | 38.67 | 36.50 | 40.09 | 47.25 | 28.69 | 42.76 |
 BR only | 26.29 | 24.83 | 23.55 | 25.88 | 31.16 | 17.85 | 27.97 |
 Incremental change in successful outcomes (bedaquiline + BR vs. BR) (%, relative to bedaquiline) | +54.67 | +55.78 | +55.02 | +54.87 | +51.62 | +60.78 | +52.87 |
Number of cases of acquired resistance | |||||||
 Bedaquiline + BR | 2.16 | 349.72 | 28.20 | 31.88 | 52.90 | 0.50 | 1,274.00 |
 BR only | 3.16 | 512.37 | 47.58 | 46.63 | 77.04 | 0.73 | 1,862.89 |
 Incremental change in acquired resistance (bedaquiline + BR vs. BR) (%, relative to bedaquiline) | -31.59 | -31.75 | -40.8 | -31.62 | -31.34 | -32.22 | -31.61 |