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Table 2 Data collection

From: Design of the Indian NCA study (Indian national collaboration on AIDS): a cluster randomized trial to evaluate the effectiveness of integrated care centers to improve HIV outcomes among men who have sex with men and persons who inject drugs in India

 

MSM

PWID

Survey modules

 Demographics

x

x

 Peer network size

x

x

 HIV testing, care and medications (HIV care continuum)

x

x

 HIV treatment knowledge (including questions on other local HIV testing and treatment efforts)

x

x

 Substance use (drugs, alcohol), injection-related risk behavior, sexual risk behavior

x

x

 Service utilization (NSEP, OAT, condom provision)

x

x

 Tuberculosis history

x

x

 Depressive symptoms (Patient Health Questionnaire-9 [62, 65])

x

x

 Social support

x

x

 Stigma (Enacted, vicarious, felt normative, internalized MSM stigma)

x

 

 Stigma (Enacted, vicarious, felt normative, internalized PWID stigma)

 

x

 Quality of life (adapted version of EuroQOL [66])

x

x

 Acceptability of novel prevention interventions (early ART, circumcision, PrEP)

x

x

 Sexual health (including STI history)

x

 

 Hepatitis C virus and Hepatitis B virus testing, care and treatment

 

x

Laboratory testing

 HIV8

Determine HIV 1/2, Alere Medical Co., Ltd., Chiba, Japan

First Response HIV Card Test 1-2.0, PMC Medical India Pvt, Ltd, Daman, India

Signal Flow Through HIV 1 + 2 Spot/Immunodot Test kit, Span Diagnostics Ltd, Surat, India

x

x

 CD4 counta

Flow cytometry, Epics XL – MCL, Beckman Coulter Inc., USA

x

x

 HIV RNAa

RealTime HIV-1 Assay, Abbott Laboratories, Abbott Park, Illinois, USA

x

x

 BED assaya

Awareâ„¢ BEDâ„¢ EIA HIV-1 Incidence Test (IgG Capture HIV-EIA), Calypte Biomedical Corporation, Portland, OR, USA

x

x

 Avidity [67]a

GS HIV-1/HIV-2 PLUS O EIA, Biorad Laboratories, Redmond, USA using diethyl amine as the chaotropic agent

x

x

 HSV-2

Anti-HSV-2 (gG2) ELISA (IgG), Euroimmun Medizinische Labordiagnostika AG, Lubeck, Germany

x

 

 Syphilis

RPR Test Kit, Span Diagnostics Ltd. Surat, India

Immunotrep TPHA, Omega Diagnostics Limited, Scotland, UK

x

 
  1. Abbreviations: NSEP needle and syringe exchange programs, OAT opioid agonist therapy, MSM men who have sex with men, PWID people who inject drugs, ART antiretroviral therapy, PrEP pre-exposure prophylaxis, STI sexually transmitted infections
  2. aTests performed only among those who tested HIV positive. Cross-sectional estimation of HIV incidence was based on a multi-assay algorithm (MAA) validated for HIV Subtype C [68] – the predominant subtype in India that included CD4, HIV RNA, BED and Avidity [69]
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