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Table 3 Prognostic Test Characteristics for the “In-hospital Mortality for PulmonAry embolism using Claims daTa” Rule

From: External validation of a multivariable claims-based rule for predicting in-hospital mortality and 30-day post-pulmonary embolism complications

  Impact Complication TP (%) TN (%) FP (%) FN (%) Sensitivity Specificity NPV PPV AUC
Low-risk High-risk No Yes (TP/TP + FN) (TN/TN + FP) (TN/TN + FN) (TP/TP + FP) (95 % CI)
N N N N (%, 95 % CI) (%, 95 % CI) (%, 95 % CI) (%, 95 % CI)
All-Cause In-Hospital Mortality 9,259 38,272 43,764 3,762 9.4 98.0 90.6 2.0 95.2 (94.4–95.8) 20.7 (20.4–21.1) 98.0 (97.7–98.3) 9.4 (9.1–9.7) 0.66 (0.65–0.67)
All-Cause 30-Day Mortality 9,259 38,272 43,089 4,442 11.1 98.0 88.9 2.0 95.9 (95.3–96.5) 21.1 (20.7–21.5) 98.0 (97.7–98.3) 11.1 (10.8–11.5) 0.68 (0.67–0.69)
30-Day Recurrent VTE, Rehospitalization or Death From Any Cause 9,259 38,272 37,661 9,870 22.8 87.8 77.1 12.2 88.5 (87.9–89.2) 21.6 (21.2–22.0) 87.8 (87.1–88.5) 22.8 (22.4–23.3) 0.62 (0.62–0.63)
  1. AUC area under the curve statistic, CI confidence interval, FN false negative, FP false positive, IMPACT In-hospital Mortality for PulmonAry embolism using Claims daTa, N number, NPV negative predictive value, PPV positive predictive value, TN true negative, TP true positive, VTE venous thromboembolism