Randomised trials comparing different healthcare settings: an exploratory review of the impact of pre-trial preferences on participation, and discussion of other methodological challenges

Table 1 Effect of preferences on accrual and withdrawal in healthcare setting studies reporting reasons for non-participation

Key:
Grey-shaded studies used a patient preference design, all other studies used randomisation only
Numbers in brackets are % of the potentially eligible patients
^aItalicised settings are those available outside of the trial (where information to assess this is reported)
^bMay be an underestimate of patients actually eligible as ‘clinicians were reluctant to refer patients to the trial’
^cTrials stopped early
^dPatients ‘registered in the chemotherapy in the home program’
(X) Cross-over trial
LMWH low-molecular-weight heparin (subcutaneous)
SH standard heparin (intravenous)

ISSN: 1472-6963