Patient characteristics | Hospital A | Hospital B | Hospital C | All | p | ||||
---|---|---|---|---|---|---|---|---|---|
(n = 786) | (n = 96) | (n = 263) | (n = 1145) | ||||||
From HDRs | |||||||||
Age in years, mean [SD] | 82.3 | [9.2] | 77.1 | [11.0] | 79.7 | [10.2] | 81.3 | [9.8] | <0.001 |
Gender, n (%) | 0.01 | ||||||||
Male | 339 | (43.1) | 55 | (57.3) | 129 | (49.0) | 523 | (45.7) | |
Female | 447 | (56.9) | 41 | (42.7) | 134 | (51.0) | 622 | (54.3) | |
Length of stay in days, median [IQR] | 8 | [7] | 9.5 | [9.5] | 8 | [6] | 8 | [7] | <0.001 |
Comorbidity, n (%) | |||||||||
Malignant tumors | 75 | (9.5) | 11 | (11.5) | 31 | (11.8) | 117 | (10.2) | 0.53 |
Diabetes | 129 | (16.4) | 19 | (19.8) | 49 | (18.6) | 197 | (17.2) | 0.56 |
Disorders of lipoid metabolism | 44 | (5.6) | 6 | (6.3) | 27 | (10.3) | 77 | (6.7) | 0.03 |
Obesity | 23 | (2.9) | 2 | (2.1) | 13 | (4.9) | 38 | (3.3) | 0.26 |
Hematologic diseases | 127 | (16.2) | 10 | (10.4) | 50 | (19.0) | 187 | (16.3) | 0.14 |
Hypertensive diseases | 247 | (31.4) | 31 | (32.3) | 96 | (36.5) | 374 | (32.7) | 0.31 |
Previous AMI | 122 | (15.5) | 25 | (26.0) | 48 | (18.3) | 195 | (17.0) | 0.03 |
Other forms of ischemic heart disease | 257 | (32.7) | 42 | (43.8) | 72 | (27.4) | 371 | (32.4) | 0.01 |
Ill-defined descriptions and complications of heart disease | 12 | (1.5) | 4 | (4.2) | 6 | (2.3) | 22 | (1.9) | 0.14 |
Rheumatic heart disease | 50 | (6.4) | 9 | (9.4) | 15 | (5.7) | 74 | (6.5) | 0.45 |
Cardiomyopathies | 56 | (7.1) | 21 | (21.9) | 19 | (7.2) | 96 | (8.4) | <0.001 |
Other cardiac diseases | 60 | (7.6) | 21 | (21.9) | 34 | (12.9) | 115 | (10.0) | <0.001 |
Conduction disorders and cardiac dysrhythmias | 207 | (26.3) | 30 | (31.3) | 80 | (30.4) | 317 | (27.7) | 0.32 |
Cerebrovascular diseases | 121 | (15.4) | 21 | (21.9) | 50 | (19.0) | 192 | (16.8) | 0.15 |
Vascular diseases | 66 | (8.4) | 11 | (11.5) | 26 | (9.9) | 103 | (9.0) | 0.52 |
COPD | 122 | (15.5) | 19 | (19.8) | 42 | (16.0) | 183 | (16.0) | 0.56 |
Chronic nephropathies | 173 | (22.0) | 34 | (35.4) | 97 | (36.9) | 304 | (26.6) | <0.001 |
Chronic diseases of liver, pancreas and intestine | 16 | (2.0) | 1 | (1.0) | 5 | (1.9) | 22 | (1.9) | >0.99 |
Previous bypass | 14 | (1.8) | 6 | (6.3) | 18 | (6.8) | 38 | (3.3) | <0.001 |
Previous PCI | 40 | (5.1) | 9 | (9.4) | 16 | (6.1) | 65 | (5.7) | 0.20 |
Other surgery of the heart | 18 | (2.3) | 9 | (9.4) | 7 | (2.7) | 34 | (3.0) | <0.01 |
Other surgery of great vessels | 18 | (2.3) | 2 | (2.1) | 8 | (3.0) | 28 | (2.4) | 0.74 |
Previous diagnosis of heart failure | 223 | (28.4) | 34 | (35.4) | 74 | (28.1) | 331 | (28.9) | 0.34 |
From OPD | |||||||||
Previous medication use, n (%) | |||||||||
Antidiabetic drugs | 174 | (22.1) | 24 | (25.0) | 59 | (22.4) | 257 | (22.4) | 0.79 |
Drugs for cardiac therapy | 262 | (33.3) | 25 | (26.0) | 70 | (26.6) | 357 | (31.2) | 0.07 |
Drugs for obstructive airway diseases | 163 | (20.7) | 30 | (31.3) | 70 | (26.6) | 263 | (23.0) | 0.02 |
Diuretics | 457 | (58.1) | 59 | (61.5) | 159 | (60.5) | 675 | (59.0) | 0.70 |
β-blockers | 200 | (25.4) | 32 | (33.3) | 75 | (28.5) | 307 | (26.8) | 0.20 |
ACEIs/ARBs | 366 | (46.6) | 38 | (39.6) | 115 | (43.7) | 519 | (45.3) | 0.36 |
Calcium channel blockers and/or other antihypertensive drugs | 472 | (60.1) | 68 | (70.8) | 155 | (58.9) | 695 | (60.7) | 0.10 |
Statins | 383 | (48.7) | 53 | (55.2) | 131 | (49.8) | 567 | (49.5) | 0.49 |
Antiplatelet drugs | 181 | (23.0) | 25 | (26.0) | 56 | (21.3) | 262 | (22.9) | 0.63 |
From medical charts | |||||||||
Emergency department utilization, n (%) | 767 | (97.6) | 78 | (81.3) | 256 | (97.3) | 1101 | (96.2) | <0.001 |
Heart rate in bpm, mean [SD]a | 87 | [20.7] | 86 | [19.4] | 85 | [18.7] | 87 | [20.2] | 0.52 |
Systolic blood pressure in mmHg, mean [SD] | 140 | [32.8] | 139 | [32.5] | 142 | [32.3] | 140 | [32.6] | 0.67 |
Pulmonary congestion, n (%) | 666 | (84.7) | 87 | (90.6) | 241 | (91.6) | 994 | (86.8) | <0.001 |
Heart rhythm, n (%) | 0.14 | ||||||||
Sinus rhythm | 405 | (51.5) | 42 | (43.8) | 127 | (48.3) | 574 | (50.1) | |
Atrial fibrillation | 323 | (41.1) | 41 | (42.7) | 118 | (44.9) | 482 | (42.1) | |
Pacemaker rhythm | 55 | (7.0) | 13 | (13.5) | 18 | (6.8) | 86 | (7.5) | |
Bundle branch block, n (%) | 0.55 | ||||||||
No | 625 | (79.5) | 78 | (81.3) | 208 | (79.1) | 911 | (79.6) | |
Right | 72 | (9.2) | 6 | (6.3) | 30 | (11.4) | 108 | (9.4) | |
Left | 89 | (11.3) | 12 | (12.5) | 25 | (9.5) | 126 | (11.0) | |
QRS complex, mean [SD]b | 151 | [18.1] | 159 | [24.0] | 152 | [19.9] | 152 | [19.0] | 0.25 |
Serum creatinine in mg/dL, mean [SD] | 1.42 | [0.9] | 1.32 | [0.6] | 1.4 | [0.9] | 1.41 | [0.9] | 0.59 |
Chronic kidney disease stage (using MDRD formula), n (%) | 0.38 | ||||||||
1 | 60 | (7.6) | 9 | (9.4) | 32 | (12.2) | 101 | (8.8) | |
2 | 210 | (26.7) | 25 | (26.0) | 74 | (28.1) | 309 | (27.0) | |
3a | 191 | (24.3) | 24 | (25.0) | 53 | (20.2) | 268 | (23.4) | |
3b | 179 | (22.8) | 27 | (28.1) | 60 | (22.8) | 266 | (23.2) | |
4 | 122 | (15.5) | 10 | (10.4) | 35 | (13.3) | 167 | (14.6) | |
5 | 24 | (3.1) | 1 | (1.0) | 9 | (3.4) | 34 | (3.0) | |
Sodium in mmol/l, mean [SD] | 139 | [5.8] | 139 | [3.7] | 138 | [4.8] | 139 | [5.4] | <0.001 |
Hemoglobin in g/dL, mean [SD] | 12.1 | [2.2] | 12.1 | [1.9] | 12.1 | [2.0] | 12.1 | [2.1] | >0.90 |
Previously implanted pacemaker, n (%) | 80 | (10.2) | 21 | (21.9) | 29 | (11.0) | 130 | (11.4) | <0.01 |
Previously implanted cardioverter defibrillator, n (%) | 13 | (1.7) | 10 | (10.4) | 9 | (3.4) | 32 | (2.8) | <0.001 |