Frequency and clinical relevance of potential cytochrome P450 drug interactions in a psychiatric patient population – an analysis based on German insurance claims data

Table 3 Most frequently prescribed drugs that interact with CYP450 enzymes by ATC codes

	All patients (n = 1221)
Prescribed drugs by ATC codes	Frequency	Number of patients (%)
M01 – Anti-inflammatory/antirheumatic products	3313	713 (58.40)
N06 – Antidepressants	6249	635 (52.0)
N05 – Antipsychotics	5879	471 (38.58)
A02 – Drugs for acid-related disorders	3050	448 (36.69)
N02 – Analgesics	1473	250 (20.48)
J01 – Antibacterials for systemic use	247	146 (11.96)
C10 – Lipid-modifying agents	941	137 (11.22)
C08 – Calcium channel blockers	1195	131 (10.73)
R05 – Cough and cold preparations	165	100 (8.19)
N03 – Antiepileptics	523	80 (6.55)
…
Sum	25,211	N/A

The relative frequency (n) and number of patients who were prescribed the drug (n, %) are shown. Note that patients could be prescribed several drug classes

ISSN: 1472-6963