Skip to main content

Advertisement

Table 3 The effectiveness, total cost, and incremental cost-effectiveness by vaccination strategy against cervical cancer due to HPV types 16 and 18

From: The economic evaluation of human papillomavirus vaccination strategies against cervical cancer in women in Lao PDR: a mathematical modelling approach

Number Options Total cost per 1000 women Cancer per 1000 women Cancer reduction (%) DALY averted per 1000 women Cost-effective ratio (cancer reduction) Cost-effective ratio (DALY averted) ICER (cancer reduction) ICER (DALY averted)
1. No vaccination with current screening 4497 3.4 - - - - - -
2. 10 years old girls 21,599 0.7 77.9 31.1 8000 695 6334 550
3. 10 years old girls + catch-up girls aged 11–25 years old 27,807 0.4 86.8 35.1 9269 792 20,693 1559
4. 10 years old girls + boys 38,030 0.6 81.3 32.6 13,582 1167 D D
5. 10 years old girls + catch-up girls aged 11–75 years old 39,059 0.3 91.4 37.0 12,600 1056 112,520 5840
6. 10 years old girls + boys + catch-up girls aged 11–25 years old 44,263 0.4 87.4 35.3 14,754 1254 D D
7. 10 years old girls + boys + catch-up girls and boys aged 11–25 years old 50,210 0.4 88.7 35.9 16,737 1399 D D
8. 10 years old girls + boys + catch-up girls aged 11–75 years old 55,520 0.3 91.4 37.0 17,910 1501 D D
9. 10 years old girls + boys + catch-up girls and boys aged 11–75 years old 72,723 0.3 91.8 37.2 23,459 1955 D 168,320
  1. Note: The cost-effectiveness ratio was a comparison of an option and the baseline scenarios (no vaccination with current screening). The incremental cost of effectiveness ratio expressed as cancer prevented or DALY averted is listed in order of increasing cost. In non-dominant strategy, the ICER was calculated by devising different cost to different effectiveness. ICERs is comparing the option to the next best alternative option. The D refers to strong dominance, which is expressed as higher cost, but lower effectiveness than alternative options. The currency is 2013 international dollars, using purchasing power parity
  2. The GDP per capita in 2013 was about 4822 international dollars [30]