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Table 1 Designation of Levels of Evidence

From: What is the effectiveness of the support worker role for people with dementia and their carers? A systematic review

Designation of levels of evidence
Level I Evidence obtained from a systematic review of all relevant randomised controlled trials
Level II Evidence obtained from at least one properly designed randomised controlled trial
Level III-1 Evidence obtained from well-designed pseudo-randomised controlled trials (alternate allocation or some other method)
Level III-2 Evidence obtained from comparative studies with concurrent controls and allocation not randomised (cohort studies), case-control studies, or interrupted time series with a control group
Level III-3 Evidence obtained from comparative studies with historical control, two or more single-arm studies, or interrupted time series without a parallel control group
Level IV Evidence obtained from case series, either post-test or pre-test and post-test