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Table 2 Overview on pros and cons of different outcome indicators in economic evaluations of health promotion for older people

From: Economic evaluation of health promotion for older people-methodological problems and challenges

Outcome Indicators

Cons

Pros

Cost effectiveness analysis (CEA)

Natural indicators

- Effects are reduced to a single parameter

- Not all effects are covered (e.g. intersectoral effects)

- Relevant health promotion outcomes are often difficult to operationalize

- Often proxy outcomes are used (causality to patient-relevant endpoints has to be proven)

- Comparability of different interventions is very limited

- Depending on the operationalization mostly easy and clearly measurable

- Disease specific comparisons are very easily possible

- Even small health gains can be documented

- Simple and straightforward comparability of the one given indicator

Cost utility analysis (CUA)

Aggregated indicators in general

- Aggregation of different aspects will always represent a limited perspective

- Multidimensionality of effects can be covered

- Different types of interventions can be compared

e.g. QALY

- Only health related

- Social benefits are not covered

- Intersectoral benefits are not covered

- The linear conjunction of time and quality is set externally (not preference based)

- Limited comparability for HPA

- Small health gains are measured poorly

- Does not reflect preferences of older people appropriately

- May discriminate against older people

- Widely accepted reference standard and well established instrument that is used in many economic evaluations

e.g. ICE-CAP-O

- So far not widely validated

- No comparison across age groups possible

- Limited in capturing health dimensions

- Developed according to preference weights of older people

Cost benefit analysis (CBA)

Measurement of health costs avoided only

- Health gains or social benefits are attributed no value

- Subjective elements are excluded

- Allows the comparison of measures in different fields of policy

Monetary valuation of outcomes

e.g. by willingness to pay

- Political reservations against monetary valuation of health benefits

- HPA have features of public goods, resulting in low willingness-to-pay

- Results are not independent of who is asked: thus an age bias is possible

- Willingness to pay is dependent on ability to pay

- Allows the comparison of measures in different fields of policy

- Non-health benefits can be included

Cost consequence analysis (CCA)

No standalone method

CEA or CUA with multiple endpoints

- Limited comparability of different interventions

- Complex results may be difficult to interpret

- Very transparent

- Intersectoral costs and benefits can be covered

- Contentious cost categories can be included

- Broadly spread effects are at least described qualitatively

- Description of equity effects can be included

- Enables decision makers to decide based on a differentiated assessment of the various effects or benefits

- Allows the setting of specific priorities