Systematic review of the health and societal effects of medication organisation devices

Table 4 Effect of MODs on medication adherence

Study	Design	Adherence measure	n MOD	n Control	Adherence MOD	Adherence control	p-value
Becker 1986 [20]	RCT	% participants taking > 80 % of doses	86	85	84	75.3	> 0.05
Crome 1982 [27]	RCT	% doses missed	40	38	26.1	26.2	> 0.05
Huang 2000a [23]	RCT	% participants > 90 % of doses	90	94	91	94	Not stated
Huang 2000a [23]	RCT	Median % of doses taken		94	100	99	0.63
Huang 2000b [23]	RCT	% participants taking > 90 % of doses	148	149	87	93	0.005*
Huang 2000b [23]	RCT	Median % of doses taken			99	99	> 0.05
MacIntosh 2007 [28]	RCT	% participants taking 100 % of doses	21	21	81	86	Not stated
Petersen 2007 [24]	Prospective	Increase in % doses taken			4.1 %	-	< 0.05*
Rehder 1980 [25]	RCT	% participants taking > 95 % of doses	25	25	89	47	< 0.01*
Wong 1987 [22]	RCT	% doses missed	17	17	2.04	9.17	< 0.01*

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