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Table 3 Impact of MODs on health outcome

From: Systematic review of the health and societal effects of medication organisation devices

Study Design Outcome measure Change in outcome n MOD n control p-value
Becker 1986 [20] RCT Diastolic blood pressure β = 1.45 86 85 0.259
Huang 2000a [23] RCT Change in Vitamin C serum concentration -0.9 (mg/dl) 90 94 0.47
Change in Vitamin E serum concentration -2.4 (mg/dl)    0.06*
Huang 2000b [23] RCT Change in Vitamin E serum concentration 0.9 (mg/dl) 148 149 0.53
Petersen 2007 [24] Prospective Viral Load 0.36 mean log10 copies/mL. Increased odds of viral load below 400 copies/ml OR 1.91    <0.05*
Rehder 1980 [25] RCT Change in diastolic blood pressure 1 mm Hg 25 25 > 0.05
Change in systolic blood pressure Not reported    > 0.05
Roberts 2004 [18] Cross-section Number of adverse drug reactions (ADRs) Non-MOD group reported more ADRs (47.79 %) vs non-pharmacist filled MOD group (43.24 %) and pharmacist filled MOD group (32.56 %)    0.022*
The 14 item Older Americans Resource Scale for Instrumental Activities of Daily Living (OARS-IADL) Pharmacist filled MOD group had lower ability scores (10.25) vs non-pharmacist filled MOD group (12.70) and non-MOD group (12.34)    0.001*
Simmons 2000 [26] RCT Change in diastolic blood pressure -5.9 mm Hg 36 32 0.0041*
Change in systolic blood pressure -1.0 mm Hg    0.89
Change in HbA1c -0.8 %    0.026*
  1. *indicates a significance level of p < 0.05
  2. n Mod indicates the number of participants in the group utilizing a MOD
  3. n control indicates the number of participants in the group not utilizing a MOD