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Table 3 Drug-related problems addressed during PMC at T-0 in intervention group (N = 258)

From: Impact of a community pharmacist-led medication review on medicines use in patients on polypharmacy - a prospective randomised controlled trial

  N %
Drug-related problems   
 Potential 149 58
 Manifest 109 42
Urgency rated by the study pharmacist   
 High 36 14
 Medium 113 43
 Low 109 43
Recommendation accepted by patient   
 Yes 219 85
 No 25 10
 Unclear 14 5
Causes of pharmacists’ interventions   
 Insufficient adherence 69 26.7
 Patient needs information about safe and effective use of his medicines 50 19.4
 Patient needs information about potential medicines’ adverse drug reaction 19 7.4
 Inappropriate timing or frequency of administration 18 7.0
 Under-dosed therapy 15 5.8
 Drug-drug/drug-food interaction 14 5.4
 Adverse effect 12 4.7
 Inappropriate therapy duration 10 3.9
 Inappropriate drug administration 9 3.5
 Patient needs information about lifestyle, nutrition or empowerment 8 3.1
 Not received treatment 7 2.7
 More cost-effective therapy available 5 1.9
 No concordance with guidelines or contraindication 4 1.6
 No dose adjustment because of pathological changes (renal/liver failure) 4 1.6
 Not indicated drug or duplication 3 1.2
 Incomplete patient documentation 3 1.2
 Over-dosed therapy 3 1.2
 Prescribed drug not available 2 0.8
 Inappropriate monitoring 1 0.4
 Not classifiable 2 0.8
Description of pharmacist's interventions   
 Counseling of patient, training 152 58.9
 Optimisation of administration 40 15.5
 Information to other caregivers 24 9.3
 Dose adjustment 12 4.7
 Substitution of a therapy 10 3.9
 Therapy started/restarted 7 2.7
 Therapy stopped 7 2.7
 Therapy monitoring 3 1.2
 Clarification in the patient history 2 0.8
 Not classifiable 1 0.4