|
Covariates
| |
No. CRC deaths/total
|
Stages A-C (n = 3716)
|
|---|
|
HR
|
95 % CI
|
p-value
|
|---|
|
Site
|
Colon
|
523/2409
|
1.00
|
-
|
-
|
|
Rectum
|
302/1307
|
0.94
|
0.78-1.14
|
0.538
|
|
Stage dukes
|
A
|
55/933
|
1.00
|
-
|
-
|
|
B
|
250/1438
|
2.93
|
2.18-3.94
|
0.000
|
|
C
|
520/1345
|
6.72
|
4.92-9.17
|
0.000
|
|
Grade
|
Low
|
12/104
|
1.00
|
-
|
-
|
|
Intermediate
|
512/2779
|
1.09
|
0.61-1.95
|
0.779
|
|
High
|
262/670
|
2.13
|
1.18-3.87
|
0.013
|
|
Unknown
|
39/163
|
1.59
|
0.82-3.07
|
0.172
|
|
Age group
|
50-59
|
172/758
|
1.00
|
-
|
-
|
|
60-69
|
282/1317
|
1.08
|
0.89-1.31
|
0.433
|
|
70-79
|
371/1641
|
1.12
|
0.93-1.36
|
0.240
|
|
Sex
|
Female
|
348/1604
|
1.00
|
-
|
-
|
|
Male
|
477/2112
|
1.09
|
0.94-1.26
|
0.243
|
|
Private Insurance
|
No
|
352/1625
|
1.00
|
-
|
-
|
|
Yes
|
473/2091
|
1.07
|
0.92-1.24
|
0.378
|
|
Comorbidity
|
None
|
580/2672
|
1.00
|
-
|
-
|
|
One (not severe)
|
142/653
|
0.94
|
0.77-1.13
|
0.504
|
|
Multiple / severe
|
103/391
|
1.29
|
1.02-1.62
|
0.032
|
|
SES quintile
|
Low
|
216/890
|
1.00
|
-
|
-
|
|
Low-mid
|
164/749
|
0.98
|
0.79-1.20
|
0.819
|
|
Middle
|
142/678
|
0.80
|
0.63-1.00
|
0.048
|
|
Mid-high
|
169/730
|
1.00
|
0.80-1.24
|
0.967
|
|
High
|
134/669
|
0.80
|
0.63-1.01
|
0.057
|
|
Residence
|
Urban
|
578/2624
|
1.00
|
-
|
-
|
|
Outer urban
|
74/374
|
0.96
|
0.74-1.23
|
0.724
|
|
Rural
|
117/515
|
0.94
|
0.75-1.17
|
0.561
|
|
Remote
|
56/203
|
1.35
|
1.01-1.80
|
0.040
|
|
Surgerya
|
No
|
41/96
|
1.00
|
-
|
-
|
|
Yes
|
784/3620
|
0.38
|
0.26-0.56
|
0.000
|
|
Radiotherapya
|
No
|
656/3217
|
1.00
|
-
|
-
|
|
Yes
|
169/499
|
1.48
|
1.16-1.88
|
0.002
|
|
Chemotherapya
|
No
|
399/2487
|
1.00
|
-
|
-
|
|
Yes
|
426/1229
|
1.11
|
0.92-1.35
|
0.284
|
|
Diagnosis year
|
(continuous)
|
825/3716
|
0.93
|
0.90-0.97
|
0.002
|
- CRC patients age 50-79 years diagnosed in South Australia 2003–2008
- Analysis with multiply imputed stage and grade, where missing, revealed similar results (i.e. identical patterns with regard to significant associations and approximately equivalent point estimates for all HRs)
- aTreatments received within 12 months of diagnosis
