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Table 5 Multivariate competing risks regression analysis for risk of death from CRC, for stages A-C

From: Sociodemographic disparities in survival from colorectal cancer in South Australia: a population-wide data linkage study

Covariates

 

No. CRC deaths/total

Stages A-C (n = 3716)

HR

95 % CI

p-value

Site

Colon

523/2409

1.00

-

-

Rectum

302/1307

0.94

0.78-1.14

0.538

Stage dukes

A

55/933

1.00

-

-

B

250/1438

2.93

2.18-3.94

0.000

C

520/1345

6.72

4.92-9.17

0.000

Grade

Low

12/104

1.00

-

-

Intermediate

512/2779

1.09

0.61-1.95

0.779

High

262/670

2.13

1.18-3.87

0.013

Unknown

39/163

1.59

0.82-3.07

0.172

Age group

50-59

172/758

1.00

-

-

60-69

282/1317

1.08

0.89-1.31

0.433

70-79

371/1641

1.12

0.93-1.36

0.240

Sex

Female

348/1604

1.00

-

-

Male

477/2112

1.09

0.94-1.26

0.243

Private Insurance

No

352/1625

1.00

-

-

Yes

473/2091

1.07

0.92-1.24

0.378

Comorbidity

None

580/2672

1.00

-

-

One (not severe)

142/653

0.94

0.77-1.13

0.504

Multiple / severe

103/391

1.29

1.02-1.62

0.032

SES quintile

Low

216/890

1.00

-

-

Low-mid

164/749

0.98

0.79-1.20

0.819

Middle

142/678

0.80

0.63-1.00

0.048

Mid-high

169/730

1.00

0.80-1.24

0.967

High

134/669

0.80

0.63-1.01

0.057

Residence

Urban

578/2624

1.00

-

-

Outer urban

74/374

0.96

0.74-1.23

0.724

Rural

117/515

0.94

0.75-1.17

0.561

Remote

56/203

1.35

1.01-1.80

0.040

Surgerya

No

41/96

1.00

-

-

Yes

784/3620

0.38

0.26-0.56

0.000

Radiotherapya

No

656/3217

1.00

-

-

Yes

169/499

1.48

1.16-1.88

0.002

Chemotherapya

No

399/2487

1.00

-

-

Yes

426/1229

1.11

0.92-1.35

0.284

Diagnosis year

(continuous)

825/3716

0.93

0.90-0.97

0.002

  1. CRC patients age 50-79 years diagnosed in South Australia 2003–2008
  2. Analysis with multiply imputed stage and grade, where missing, revealed similar results (i.e. identical patterns with regard to significant associations and approximately equivalent point estimates for all HRs)
  3. aTreatments received within 12 months of diagnosis