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Table 5 Multivariate competing risks regression analysis for risk of death from CRC, for stages A-C

From: Sociodemographic disparities in survival from colorectal cancer in South Australia: a population-wide data linkage study

Covariates   No. CRC deaths/total Stages A-C (n = 3716)
HR 95 % CI p-value
Site Colon 523/2409 1.00 - -
Rectum 302/1307 0.94 0.78-1.14 0.538
Stage dukes A 55/933 1.00 - -
B 250/1438 2.93 2.18-3.94 0.000
C 520/1345 6.72 4.92-9.17 0.000
Grade Low 12/104 1.00 - -
Intermediate 512/2779 1.09 0.61-1.95 0.779
High 262/670 2.13 1.18-3.87 0.013
Unknown 39/163 1.59 0.82-3.07 0.172
Age group 50-59 172/758 1.00 - -
60-69 282/1317 1.08 0.89-1.31 0.433
70-79 371/1641 1.12 0.93-1.36 0.240
Sex Female 348/1604 1.00 - -
Male 477/2112 1.09 0.94-1.26 0.243
Private Insurance No 352/1625 1.00 - -
Yes 473/2091 1.07 0.92-1.24 0.378
Comorbidity None 580/2672 1.00 - -
One (not severe) 142/653 0.94 0.77-1.13 0.504
Multiple / severe 103/391 1.29 1.02-1.62 0.032
SES quintile Low 216/890 1.00 - -
Low-mid 164/749 0.98 0.79-1.20 0.819
Middle 142/678 0.80 0.63-1.00 0.048
Mid-high 169/730 1.00 0.80-1.24 0.967
High 134/669 0.80 0.63-1.01 0.057
Residence Urban 578/2624 1.00 - -
Outer urban 74/374 0.96 0.74-1.23 0.724
Rural 117/515 0.94 0.75-1.17 0.561
Remote 56/203 1.35 1.01-1.80 0.040
Surgerya No 41/96 1.00 - -
Yes 784/3620 0.38 0.26-0.56 0.000
Radiotherapya No 656/3217 1.00 - -
Yes 169/499 1.48 1.16-1.88 0.002
Chemotherapya No 399/2487 1.00 - -
Yes 426/1229 1.11 0.92-1.35 0.284
Diagnosis year (continuous) 825/3716 0.93 0.90-0.97 0.002
  1. CRC patients age 50-79 years diagnosed in South Australia 2003–2008
  2. Analysis with multiply imputed stage and grade, where missing, revealed similar results (i.e. identical patterns with regard to significant associations and approximately equivalent point estimates for all HRs)
  3. aTreatments received within 12 months of diagnosis
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