Year of implementation | Intervention – mother (ARV prophylaxis) | CD4 count threshold for ART (cells/mm3) | Intervention – infant |
---|---|---|---|
2005 | Sd-NVP during labour & delivery | CD4 <200 | Sd-NVP to infants within 72 hours of birth |
2007 | AZT from 28 weeks gestation; sd-NVP + AZT + 3TC during labour; AZT + 3TC until 7 days postpartum | CD4 <200 | NVP for 1 week after birth and AZT for up to 4 weeks |
2012 | ‘Option A’: AZT from 14 weeks gestation; sd-NVP + AZT + 3TC during labour; AZT + 3TC until 7 days postpartum | CD4 <350 | NVP until 1 week after cessation of breastfeeding (or 4–6 weeks if replacement feeding) |