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Table 4 Insulin preparations (Cold-chain)

From: Evaluating the effect of a proposed logistics fee cap on pharmaceuticals in South Africa - a pre and post analysis

    

Pre-Logistics Fee Regulation Prices

Post-Logistics Fee Regulation Prices

  

Active Ingredients

O/G

Pack Size & Quantity

Ex- Man.Price in 2013

Log Fee in 21013

SEP in 2013 (VAT incl.)

Unit Price in 2013

Logistics fee/SEP %

Logistics fee with proposed cap

SEP with proposed cap (VAT incl.)

Unit Price with proposed cap

Logistics fee with proposed cap/Sep %

Change in SEP after logistics fee cap

Overall effect on SEP after logistics fee cap

Ultra-fast acting

Insulin Glulisine

O

10/1

258.79

8

304.14

30.41

2.63

19.53

317.28

31.73

6.15

13.14

Increase

Insulin aspart

O

10/1

223.63

30.19

289.36

28.94

10.44

17.42

274.79

27.48

6.34

−14.57

Decrease

Insulin Lispro

O

10/1

210.08

12.60

253.86

25.39

4.97

16.60

258.42

25.84

6.43

4.5694

Increase

Fast acting

Insulin (Dna)

O

10/1

193.64

26.14

250.56

25.06

10.43

15.62

238.56

23.86

6.55

−11.99

Decrease

Human Insulin

G

5/1

240.25

19.22

295.79

59.16

6.49

18.41

294.87

58.97

6.244

−0.92

Decrease

Regular Human Insulin (Rdna)

O

10/1

210.08

12.60

253.86

25.39

4.97

16.60

258.42

25.84

6.43

4.56

Increase

Intermediate to long acting

Human Insulin

G

5/1

240.25

19.22

295.79

59.16

6.49

18.41

294.87

58.97

6.244

−0.92

Decrease

Isophane insulin

O

10.1

233.46

31.52

302.07

30.21

10.43

18.01

286.67

28.67

6.28

−15.40

Decrease

Isophane Human Insulin (Rdna)

O

10/1

237.81

14.27

287.37

28.74

4.97

18.27

291.93

29.19

6.26

4.56

Increase

Long acting Insulin analogues

Insulin Glargine

O

3/5

505.68

23.83

603.64

40.24

3.95

25.23

605.23

40.35

4.17

1.59

Increase

Insulin Detemir

O

3/5

460.73

62.19

596.14

39.74

10.43

31.64

561.30

37.42

5.64

−34.83

Decrease

Biphasic

Biosynthetic human insulin

O

3/5

458.27

61.87

592.96

39.53

10.44

31.49

558.34

37.22

5.64

−34.61

Decrease

Biosynthetic Human Insulin (30 % Regular Insulin and 70 % Isophane Insulin)

O

3/5

349.13

22.29

423.41

28.23

5.26

24.95

426.45

28.43

5.85

3.04

Increase

Insulin (Human)

G

3/5

321.71

15.28

384.17

25.61

3.98

23.30

393.31

26.22

5.92

9.14

Increase

Human Insulin/ isophane insulin

G

5/1

235.21

18.82

289.59

57.92

6.49

18.11

288.79

57.76

6.27

−0.80

Decrease

Biphasic Insulin analogues

75 % Insulin Lispro Protamine Suspension (Npl)

O

3/5

349.12

22.28

423.39

28.23

5.26

24.95

426.43

28.43

5.85

3.04

Increase

Insulin aspart

O

3/5

417.34

56.34

539.99

35.99

10.43

29.040

508.87

33.92

5.71

−31.12

Decrease

50 % Insulin Lispro Protamine Suspension (Npl)

O

3/5

349.12

22.28

423.39

28.23

5.26

24.95

426.43

28.43

5.85

3.04

Increase

  1. All Prices are in ZAR; O = Originator brand; G = Generic brand; Originator insulin preparations: P value = 0.148; Generic insulin preparations: P value = 0.808