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Table 5 Responses to questionnaire on modified package leaflet supplemented with p-values (statins with placebo comparison)

From: Understanding adverse drug reactions in package leaflets – an exploratory survey among health care professionals

Extract of questionnaire

Frequency of muscle pain that was reported in clinical trials on statins:

 

Statins

Placebo

p-value

 Cochrane 2013 N = 37,938, primary prevention

9.5 %

9.2 %

0.40

 Finegold 2014 N = 46,262, primary prevention

7.9 %

7.6 %

0.407

 Finegold 2014 N = 37,618, secondary prevention

4.8 %

4.6 %

0.558

Question: If 100 patients take this statin – in how many of them does the intake of this statin cause muscle pain?a

 Responses (No)

0

1

>1

>10

No response

 Format multiple choice

 Group 6 (n = 87) Pharmacy group

10 (12 %)

12 (14 %)

48 (55 %)

14 (16 %)

3 (3 %)

  1. aPossible answers: “0” would be the correct answer