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Table 1 Epidemiology and cost inputs

From: The cost of illness attributable to diabetic foot and cost-effectiveness of secondary prevention in Peru

Parameter Value Lower estimate Upper estimate Reference
Epidemiology
a. Total population with Type 2 diabetes mellitus 942,000 [11]
b. % diabetics at high risk for ulcer 21.90 % [12, 13]
c. Prevalence of ulcer in those at high-risk 22.18 % 15.53 % 28.84 % [9, 14, 15] Own assumption: values for lower and upper estimate +/−30 %
c1. Effectiveness (reduced prevalence) with standard care 45.00 % 30.00 % 60.00 % [9, 14, 15] Own assumption: assumed values for lower and upper estimate.
c2. Effectiveness (reduced prevalence) with standard care plus temperature monitoring 78.81 % 65.00 % 85.00 % [9, 14, 15] Own assumption: assumed values for lower and upper estimate.
d. % with ulcer receiving hospital care 30.00 % 21.00 % 39.00 % [16] Own assumption: values for lower and upper estimate +/−30 %
e. % with ulcer receiving outpatient wound management 70.00 % 61.00 % 79.00 % [16] Own assumption: values for lower and upper estimate.
f. % at hospital with amputation and heal 47.75 % 33.43 % 62.08 % [16] Own assumption: values for lower and upper estimate +/−30 %
f1. % with major amputation 55.80 % [16]
f2. % with minor amputation 44.20 % [16]
g. % at hospital with debridement and heal 39.45 % 25.12 % 53.77 % [16] Own assumption: values for lower and upper estimate +/−30 %
h. % at hospital that die of diabetic foot after an amputation 12.80 % [16]
Direct costs (in 2012 US dollars)
Prevention
Sub-optimal care 65 45 84 [17, 18] Other local prices. Own assumption: values for lower and upper estimate +/−30 %
Standard care 185 129 240 [17, 18] Other local prices. Own assumption: values for lower and upper estimate +/−30 %
Standard care plus temperature monitoring 406 285 528 [17, 18] Other local prices. Own assumption: values for lower and upper estimate +/−30 %
Treatment
Wound management without hospitalization 79 [17, 18] Other local prices.
Debridement 1,022 [17, 18] Other local prices.
Minor amputation 5,153 [17, 18] Other local prices.
Major amputation 7,360 5,152 9,568 [17, 18] Other local prices. Own assumption: values for lower and upper estimate +/−30 %
Indirect costs (in 2012 US dollars)
Productivity loss from premature death 6,719 Peru's basic salary in year 2012; 3 %  discount rate.