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Table 3 Comparison of QoL scores between regimens based on nevirapine or efavirenz over the follow-up period using GEE

From: Quality of life in patients treated with first-line antiretroviral therapy containing nevirapine or efavirenz in Uganda: a prospective non-randomized study

QoL summary score

β coefficient (95 % CI)

β coefficient (95 % CI)

OR (95 % CI)

OR (95 % CI)

unadjusted

Adjusted

PHS

  

CD4 count <100 cells/μl

  

NVP

Ref

Ref

EFV

−1.61(−2.82 to −0.40)

−1.61 (−2.74 to −0.49)a

P = 0.11d

CD4 count 101–250 cells/μl

  

NVP

Ref

Ref

EFV

0.17 (−0.70 to 1.05)

0.82 (0.22 to 1.43)a

P = 0.76d

CD4 count >250 cells/μl

  

NVP

Ref

Ref

EFV

0.97 (−0.35 to 2.30)

−1.33 (−5.66 to 3.00)a

P = 0.90d

MHS

  

CD4 count <100 cells/μl

  

NVP

Ref

Ref

EFV

−0.18 (−1.18 to 0.82)

−0.39 (−1.40 to 0.62)b

P = 0.91d

CD4 count 101–250 cells/μl

  

NVP

Ref

 

EFV

−0.09 (−0.93 to 0.75)

0.16 (−0.66 to 0.98)b

P = 0.78d

CD4 count >250 cells/μl

  

NVP

Ref

Ref

EFV

−0.84 (−2.09 to 0.42)

−0.75 (−2.01 to 0.51)b

P = 0.65d

GPGI

  

CD4 count <100 cells/μlEFV versus NVP

  
 

−0.59 (0.31 to 1.13)

0.51 (0.25 to1.04)c

P = 0.54d

CD4 count 101–250 cells/μl

  

EFV versus NVP

0.85 (0.54 to 1.33)

0.98 (0.60 to 1.56)c

P = 0.08d

CD4 count >250 cells/μl

  

EFV versus NVP

1.30 (0.66 to 2.56)

1.39 (0.66 to 2.90)c

P = 0.08d

  1. aadjusted for age, study visit, diagnosis of depression, income per month, WHO stage, education level and opportunistic infection
  2. badjusted for sex, age, study visit, WHO stage, marital status, social support and level of education
  3. cadjusted for sex, age, study visit, WHO stage, education level, income per month, depression, employment status, alcohol use, social support and opportunistic infection
  4. dP value for interaction term (time*ART regimen)