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Table 5 Healthcare resource utilization for ICU patients with S. aureus or P. aeruginosa pneumonia versus controls through 90 days post index hospitalization

From: Healthcare utilization and costs associated with S. aureus and P. aeruginosa pneumonia in the intensive care unit: a retrospective observational cohort study in a US claims database

 

Cohorts of interest

S. aureus pneumonia vs No pneumonia

P. aeruginosa pneumonia vs No pneumonia

No pneumonia

S. aureus pneumonia

P. aeruginosa pneumonia

Odds Ratio/Differencea

P Valuea

Odds Ratio/Differenceb

P Valueb

(95 % CI)

(95 % CI)

No. of patients completing 90 day follow up periodc

n = 189,597

n = 1685

n = 687

    

All-cause inpatient hospitalizations

       

No. (%) of patients with ≥1 event

44,246 (23.3)

641 (38.0)

295 (42.9)

2.02 (1.83, 2.23)

<.001

2.48 (2.13, 2.88)

<.001

Mean (SD) events per patient with at least 1 event

1.5 (1.0)

1.9 (2.0)

2.0 (1.9)

0.45 (0.34, 0.56)

<.001

0.46 (0.31, 0.63)

<.001

Mean (SD) length of stay per patient with at least 1 event

7.8 (10.7)

14.7 (18.4)

17.5 (19.8)

6.96 (5.82, 8.19)

<.001

9.79 (7.85. 11.97)

<.001

No. (%) of patients with ≥1 hospitalization for pneumonia due to S. aureus

112 (0.06)

64 (3.8)

20 (2.9)

66.80 (48.95, 91.17)

<.001

50.74 (31.34, 82.14)

<.001

No. (%) of patients with ≥1 hospitalization for pneumonia due to P. aeruginosa

63 (0.03)

29 (1.7)

59 (8.6)

52.69 (33.85, 82.01)

<.001

282.61(196.46, 406.55)

<.001

ICU stays

       

No. (%) of patients with ≥1 event

9,399 (5.0)

163 (9.7)

97 (14.1)

2.05 (1.75, 2.42)

<.001

3.15 (2.54, 3.91)

<.001

Mean (SD) events per patients with at least 1 event

1.1 (0.4)

1.1 (0.3)

1.2 (0.5)

-0.02 (-0.17, 0.15)

.80

0.10 (-0.10, 0.34)

.37

Mean (SD) length of stay per patients with at least 1 event

1.6 (3.6)

3.5 (10.1)

1.9 (3.6)

1.92 (1.46, 2.44)

<.001

0.34 (-0.01, 0.77)

.06

No. (%) of patients with ≥1 hospitalization for pneumonia due to S. aureus

66 (0.03)

25 (1.5)

9 (1.3)

43.25 (27.23, 68.70)

<.001

38.13 (18.93, 76.81)

<.001

No. (%) of patients with ≥1 hospitalization for pneumonia due to P. aeruginosa

32 (0.02)

17 (1.0)

30 (4.4)

60.38 (33.46, 108.94)

<.001

270.47 (163.40, 447.69)

<.001

  1. CI confidence interval, ICU intensive care unit
  2. aOdds ratio (OR) from Chi-square test is used for categorical variables, negative binomial models are used to test for differences between means for count variables (number of events and length of stay). Statistical comparisons are comparing Cohort 3 (pneumonia due to S. aureus) with Cohort 1 (no pneumonia, reference group); ie, Difference = mean (Cohort 3) − mean (Cohort 1) and OR = Odds (Cohort 3)/Odds (Cohort 1)
  3. bOdds ratio (OR) from Chi-square test is used for categorical variables, negative binomial models are used to test for differences between means for count variables (number of events and length of stay). Statistical comparisons are comparing Cohort 4 (pneumonia due to P. aeruginosa) to Cohort 1 (no pneumonia, reference group); ie, Difference = mean (Cohort 4) – mean (Cohort 1) and OR = Odds (Cohort 4)/Odds (Cohort 1)
  4. cPost-index utilization results include only patients who survived to the end of the 30 or 90 day post-discharge period
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BMC Health Services Research

ISSN: 1472-6963

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