
Cohorts of interest

Comparisons



S. aureus pneumonia vs No pneumonia

P. aeruginosa pneumonia vs No pneumonia



No pneumonia (n = 201,394)

S. aureus pneumonia (n = 2275)

P. aeruginosa pneumonia (n = 1007)

Odds Ratio/Difference^{a} (95 % CI)

P Value^{a}

Odds Ratio/Difference^{b} (95 % CI)

P Value^{b}


Index hospitalization mortality
       
No. (%) of patients

6,188 (3.1)

363 (16.0)

203 (20.2)

5.99 (5.34, 6.72)

<.001

7.97 (6.81, 9.31)

<.001

Postindex mortality
       
No. (%) of patients

5,609 (2.8)

227 (10.0)

117 (11.6)

3.87 (3.37, 4.45)

<.001

4.59 (3.78, 5.57)

<.001

Mean (SD) time to death^{c}

32.8 (27.1)

25.5 (25.8)

28.1 (28.4)

7.30 (10.51, 3.63)

<.001

4.69 (9.44, 1.02)

.10

Survival rate:
   
3.75 (3.28, 4.28)

<.001

4.40 (3.66, 5.28)

<.001

30 days (%)

98.5

93.4

92.9
    
90 days (%)

97.2

90.0

88.4
    
Index + postindex mortality
       
No. (%) of patients

11,797 (5.9)

590 (25.9)

320 (31.8)

5.63 (5.11, 6.19)

<.001

7.49 (6.55, 8.56)

<.001

Mean (SD) time to death^{c}

24.9 (28.3)

46.4 (47.6)

63.5 (59.3)

21.53 (17.39, 26.07)

<.001

38.57 (31.08, 47.07)

<.001

 CI confidence interval, ICU intensive care unit
 ^{a}Odds ratio (OR) from Chisquare test is used for categorical variables, negative binomial models are used to test for differences between means for count variables (number of events and length of stay). Statistical comparisons are comparing Cohort 3 (pneumonia due to S. aureus) with Cohort 1 (no pneumonia, reference group); ie, Difference = mean (Cohort 3) − mean (Cohort 1) and OR = Odds (Cohort 3)/Odds (Cohort 1)
 ^{b}Odds ratio (OR) from Chisquare test is used for categorical variables, negative binomial models are used to test for differences between means for count variables (number of events and length of stay). Statistical comparisons are comparing Cohort 4 (pneumonia due to P. aeruginosa) with Cohort 1 (no pneumonia, reference group); i.e., Difference = mean (Cohort 4) − mean (Cohort 1) and OR = Odds (Cohort 4)/Odds (Cohort 1)
 ^{c}Including only patients with mortality