| |
Morphine equivalents milligrams/30 days
|
|---|
| |
Mean
|
Standard deviation
|
|---|
|
Pregabalin
| | |
|
Pre-index
|
525.7
|
1,682.0
|
|
Post-index
|
585.9
|
1,539.8
|
|
Difference
|
60.2
|
899.2
|
|
Duloxetine
| | |
|
Pre-index
|
442.6
|
1,208.0
|
|
Post-index
|
619.5
|
1,652.7
|
|
Difference
|
176.9
|
936.5
|
|
Difference-in-difference comparison*
|
60.2 vs. 176.9
| |
|
Statistical difference*
|
t = −1.90, p = 0.058
|
- *Difference in Difference t-statistic derived from a generalized linear mixed model with an identity link and a Gaussian distribution adjusting for baseline demographics, Deyo-Charlson comorbidity index, and pre- and post-index non-opioid pain medication utilization.
