| Pregabalin | Duloxetine |  | ||
---|---|---|---|---|---|
 | N = 446 | N = 446 |  | ||
 | n | % | n | % | P value* |
Abdominal pain/cramping | 106 | 23.8 | 107 | 24.0 | 0.9374 |
Anxiety disorder | 57 | 12.8 | 57 | 12.8 | 1 |
Arthritis | 186 | 41.7 | 198 | 44.4 | 0.4171 |
Back pain with neuropathic involvement | 123 | 27.6 | 126 | 28.3 | 0.8228 |
Causalgia and other painful neuropathies | 109 | 24.4 | 112 | 25.1 | 0.8160 |
Depression | 77 | 17.3 | 71 | 15.9 | 0.5892 |
Diabetes | 388 | 87.0 | 397 | 89.0 | 0.3537 |
Epilepsy | 9 | 2.0 | 10 | 2.2 | 0.8166 |
Fatigue | 133 | 29.8 | 136 | 30.5 | 0.8268 |
Irritable bowel syndrome | 6 | 1.3 | 6 | 1.3 | 1 |
Migraine headache | 9 | 2.0 | 10 | 2.2 | 0.8166 |
Muscle weakness | 50 | 11.2 | 49 | 11.0 | 0.9151 |
Neck pain with neuropathic involvement | 36 | 8.1 | 42 | 9.4 | 0.4770 |
Other back pain | 165 | 37.0 | 168 | 37.7 | 0.8355 |
Other mental disorders | 1 | 0.2 | 1 | 0.2 | ** |
Other musculoskeletal pain | 333 | 74.7 | 338 | 75.8 | 0.6982 |
Other neck pain (spinal) | 57 | 12.8 | 63 | 14.1 | 0.5560 |
Sleep disorders | 111 | 24.9 | 114 | 25.6 | 0.8171 |
Substance abuse or dependence | 57 | 12.8 | 59 | 13.2 | 0.8422 |
Tension headache | 5 | 1.1 | 4 | 0.9 | ** |
Thinking/memory loss | 12 | 2.7 | 8 | 1.8 | 0.3657 |
Trigeminal nerve disorders | 2 | 0.4 | 0 | 0.0 | ** |
 | Mean | SD | Mean | SD |  |
Deyo-Charlson Comorbidity Index score | 2.6 | 2.2 | 2.7 | 2.2 | 0.3058 |