Validation of the Adherence Barriers Questionnaire – an instrument for identifying potential risk factors associated with medication-related non-adherence

Table 6 Spearman rank correlation among the ABQ (and subscales), the AMRS score and the TTR for the subgroup of patients without a high probability of social desirability bias

	Modified adherence to refills and medications scale (ARMS)	Time in therapeutic range (TTR)
	N = 298⁺	N = 275^÷
ABQ	0.468*	- 0.189**
Subscale 1 (intentional barriers)	0.435*	- 0.197**
Subscale 2 (medication-/health care system-related barriers)	0.373*	- 0.174**
Subscale 3 (unintentional barriers)	0.332*	- 0.101***

⁺Subgroup of patients with a social desirability score < 5 and with complete ABQ as well as modified ARMS data.
^÷Subgroup of patients with a social desirability score < 5 and with complete ABQ, who received vitamin K antagonist and had at least 2 INR values available.
*p < 0.001 (2-tailed).
**p < 0.005 (2-tailed).
***p = 0.094 (2-tailed).
ABQ: Adherence Barriers Questionnaire, ARMS: Adherence to Refills and Medications scale, TTR: Time in Therapeutic Range, INR: International Normalized Ratio.

ISSN: 1472-6963