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Table 1 Dispensing patterns of branded and generic drugs

From: The changing patterns of dispensing branded and generic drugs for the treatment of gastroesophageal reflux disease between 2006 and 2011 in Japan: a retrospective cohort study

Dispensing pattern

Patients n (%)

Male n (%)

Age (years) mean ± SD

Initial dispensing

All dispensing

% of PPIs

% of H2RAs

% of PPIs

% of H2RAs

1. Branded (once)

6328 (43.4)

3256 (51.5)

41.3 ± 11.8

82.0

18.0

n/a

n/a

2. Generic (once)

1385 (9.5)

644 (46.5)

40.7 ± 11.8

70.8

29.2

n/a

n/a

3. Branded (≥twice)

4979 (34.1)

2476 (49.7)

45.0 ± 12.3

79.7

20.3

79.0

21.0

4. Generic (≥twice)

1000 (6.9)

476 (47.6)

45.3 ± 12.5

76.6

23.4

77.7

22.3

5. Branded to Generic (switched once)

486 (3.3)

261 (53.7)

47.3 ± 12.1

82.9

17.1

80.5

19.5

6. Generic to Branded (switched once)

198 (1.4)

106 (53.5)

43.9 ± 12.4

58.6

41.4

78.7

21.3

7. Started with Branded (switched multiple times)

142 (1.0)

62 (43.7)

46.3 ± 12.6

81.0

19.0

81.5

18.5

8. Started with Generic (switched multiple times)

72 (0.5)

42 (58.3)

47.5 ± 12.7

62.5

37.5

76.5

23.5

  1. SD: standard deviation, PPIs: proton pump inhibitors, H2RAs: histamine H2-receptor antagonists.