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Table 1 Excerpt of the internal guideline: recommendations on treatment of bronchial obstruction

From: How to improve prescription of inhaled salbutamol by providing standardised feedback on administration: a controlled intervention pilot study with follow-up

 

Inhaler device

Children <12 years

Children >12 years

Interval (minimum)

Regular dosage regimen

Nebulization (1 drop = 0,25 mg)

1-2 drops per life year, min. single dose 3 drops (recommendation by the local Pediatric Pneumology Section), max. single dose 8 drops; 3-4 times/day

5-10 drops, 3-5 times/day, max. daily dose 50 drops

4 hours

Metered dose inhaler (MDI) (1 puff = 100 μg)

1 puff 3-4 times/day; as needed up to 6 puffs/day

1-2 puffs 3-4 times/day; as needed up to 12 puffs/day

3 hours

High dosage regimen

• Recommendation in cases of severe obstruction or insufficient inhalation technique according to the local Pediatric Pneumology Section: 2 puffs 6 times/day (MDI)

• Note: inform family/carer on off-label use; higher doses need to be discussed with a senior physician

General remarks

• Children <5 years: prefer MDI with spacer (use facemask if necessary)

• Increased single dose/frequency possible as needed for symptoms in individual cases (off-label)

• Good response to salbutamol/recovery from symptoms: reduce interval between inhalations to 3 hours (MDI) or 4 hours (nebulization)

• No oral β2-agonists in acute situations

Disclaimer

• The recommendations cover only routine care situations, in individual cases therapy has to be adjusted to the individual needs.

• The therapy decision is the sole responsibility of the prescribing physician.

• This information does not replace the approved summary of product characteristics.

  1. Legend: if not stated otherwise: dosage approved by the national authority.