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Table 5 Adjusted 1 relative risk estimates of receiving radiotherapy treatment after breast conserving surgery

From: Treatment variation in patients diagnosed with early stage breast cancer in Alberta from 2002 to 2010: a population-based study

 

Adjusted1relative risk estimates (95% confidence interval)

 

Stage I

Stage II

Stage III

Age at diagnosis

P < 0.001

P < 0.001

P = 0.37

<50

1.00

1.00

1.00

50-59

1.00 (0.98, 1.02)

0.99 (0.96, 1.02)

1.02 (0.96, 1.10)

60-69

0.99 (0.96, 1.01)

1.02 (0.99, 1.04)

1.02 (0.92, 1.10)

70-79

0.94 (0.91, 0.97)

1.01 (0.96, 1.04)

1.03 (0.90, 1.11)

≥80

0.49 (0.43, 0.56)

0.53 (0.43, 0.64)

0.64 (0.34, 1.05)

Geography of surgery

P = 0.09

P = 0.07

P = 0.87

Calgary

1.00

1.00

1.00

South

0.96 (0.91, 1.00)

0.94 (0.86, 1.00)

1.03 (0.89, 1.11)

Central

0.96 (0.91, 1.01)

0.97 (0.90, 1.01)

1.03 (0.86, 1.11)

Edmonton

0.99 (0.98, 1.01)

1.00 (0.98, 1.03)

1.03 (0.97, 1.10)

North

0.95 (0.88, 1.00)

0.92 (0.81, 1.01)

1.03 (0.82, 1.12)

Year of diagnosis

P = 0.25

P = 0.15

P = 0.96

2002 - 2004

1.00

1.00

1.00

2005 - 2007

0.99 (0.97, 1.01)

0.97 (0.94, 1.00)

1.00 (0.94, 1.06)

2008 - 2010

1.00 (0.98, 1.02)

0.98 (0.96, 1.01)

0.99 (0.92, 1.06)

ER/PR Status & Hormone therapy

P < 0.001

P < 0.001

P < 0.001

ER/PR positive & received hormone

1.00

1.00

1.00

ER/PR positive & no hormone

0.86 (0.83, 0.89)

0.59 (0.49, 0.68)

0.35 (0.16, 0.60)

ER/PR negative

0.94 (0.91, 0.97)

0.89 (0.84, 0.93)

0.95 (0.85, 1.02)

Neo-adjuvant chemotherapy

P = 0.33

P = 0.04

P = 0.86

Not received

1.00

1.00

1.00

Received

0.89 (0.52, 1.05)

1.10 (1.00, 1.14)

1.03 (0.72, 1.47)

Adjuvant chemotherapy

P = 0.62

P < 0.001

P < 0.001

Not received

1.00

1.00

1.00

Received

1.01 (0.98, 1.02)

1.08 (1.05, 1.13)

1.37 (1.14, 1.84)

  1. 1Adjusted for all variables in the table.