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Table 3 Adjusted 1 relative risk estimates of receiving BCS rather than mastectomy

From: Treatment variation in patients diagnosed with early stage breast cancer in Alberta from 2002 to 2010: a population-based study

 

Adjusted1relative risk estimates (95% confidence intervals)

 

Stage I

Stage II

Stage III

Age at diagnosis

P < 0.001

P < 0.001

P < 0.001

<50

1.00

1.00

1.00

50-59

1.08 (1.02, 1.14)

1.03 (0.95, 1.13)

1.10 (0.86, 1.39)

60-69

1.01 (0.95, 1.07)

0.94 (0.86, 1.03)

0.95 (0.72, 1.24)

70-79

0.87 (0.81, 0.93)

0.71 (0.63, 0.80)

0.53 (0.35, 0.77)

≥80

0.87 (0.79, 0.95)

0.62 (0.53, 0.73)

0.63 (0.41, 0.92)

Geography of surgery

P < 0.001

P < 0.001

P = 0.30

Calgary

1.00

1.00

1.00

South

0.83 (0.76, 0.90)

0.74 (0.63, 0.85)

0.92 (0.61, 1.32)

Central

0.65 (0.57, 0.72)

0.58 (0.49, 0.68)

0.62 (0.37, 0.95)

Edmonton

0.96 (0.92, 1.00)

0.91 (0.85, 0.98)

0.95 (0.77, 1.18)

North

0.88 (0.77, 0.99)

0.72 (0.58, 0.88)

0.95 (0.57, 1.45)

Year of diagnosis

P = 0.24

P = 0.40

P = 0.99

2002-2004

1.00

1.00

1.00

2005-2007

1.02 (0.97, 1.08)

1.02 (0.94, 1.11)

1.02 (0.80, 1.31)

2008-2010

1.04 (0.99, 1.09)

1.06 (0.97, 1.15)

1.02 (0.79, 1.31)

ER/PR status

P = 0.11

P = 0.34

P = 0.44

Positive

1.00

1.00

1.00

Negative

0.96 (0.90, 1.01)

0.96 (0.88, 1.04)

0.91 (0.70, 1.15)

Neo-adjuvant chemotherapy

P < 0.001

P < 0.001

P < 0.001

Not Received

1.00

1.00

1.00

Received

0.32 (0.15, 0.57)

0.57 (0.45, 0.70)

0.31 (0.21, 0.45)

  1. 1Adjusted for all variables in the table.