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Table 2 Procured expenditure/DDD (CNY) for the different PPIs (generic and originator) in the Chongqing hospital from 2004 to 2013

From: Prescribing efficiency of proton pump inhibitors in China: influence and future directions

PPIs Dosage form 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 % change overtime
Omeprazole Generic Oral 4.15 4.11 3.42 3.27 3.27 3.03 1.85     −55%
Omeprazole Generic Injection 38.89 34.29 27.16 27.87 27.25 28.09 29.75 29.41 22.91 14.50 −63%
Omeprazole Originator Oral 14.19 13.87 12.16 12.11 11.86 11.85 11.70 11.58 11.85 11.83 −17%
Omeprazole Originator Injection 73.21 70.61 65.30 64.65 62.18 62.18 61.28 60.77 56.42 45.32 −38%
Lansoprazole Generic Oral   9.92 8.33 7.69 7.79 8.10 8.21 6.88 5.74 5.17  
Lansoprazole Generic Injection        110.00 104.11 96.30 93.04  
Pantoprazole Generic Oral 9.86 9.68 8.91 8.44 8.64 8.81 8.83 7.54 6.10 5.22 −47%
Pantoprazole Generic Injection 92.15 76.74 63.24 58.68 55.31 54.05 53.72 34.13 27.51 21.68 −76%
Pantoprazole Originator Injection          109.67 108.69  
Rabeprazole Generic Oral 11.99 12.74 15.28 11.50 10.29 10.23 10.11 9.32 8.25 7.78 −35%
Rabeprazole Originator Oral 33.94 33.15 30.59 31.50 30.37 30.37      −100%
Esomeprazole Originator Oral 14.08 15.20 13.23 13.72 13.73 12.88 13.20 13.60 12.80 12.64 −10%
Esomeprazole Originator Injection      93.00 93.00 93.00 93.00 91.65 90.65  
Ilaprazole Originator Oral        32.83 32.34 32.22 32.22  
Total oral   12.35 11.91 11.60 10.43 9.84 9.74 9.98 9.24 8.12 8.16 −34%
Total injectable   68.81 64.56 50.97 49.18 41.22 40.84 42.54 47.39 53.07 55.40 −19%
Differences between injectable and oral (fold)   5.6 5.4 4.4 4.7 4.2 4.2 4.3 5.1 6.5 6.8  
  1. NB - % change over time typically refers to 2013 vs. 2004. However, this can vary depending when the different formulations were first procured. Blank cells mean no PPI available. Fold = times, e.g. total injectable PPIs in 2004 were 5.6 times more expensive per item than the equivalent oral preparations (DDD based).