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Table 2 Utility values and costing data considered in the model

From: Economic evaluation of ivabradine in the treatment of chronic heart failure in Greece

Parameters

Values

Source

Utility values

  

No hospitalization

 

SHIFT trial

NYHA I

0.82

 

NYHA II

0.74

 

NYHA III

0.64

 

NYHA IV

0.46

 

Hospitalization

 

SHIFT trial

NYHA I

−0.04

 

NYHA II

−0.07

 

NYHA III

−0.10

 

NYHA IV

−0.29

 

Drug costs per month

 

price bulletin issued by the Greek Ministry of Health [15], law 4052/2012, Government Gazette

Standard care

€35.26

Ivabradine

€40.52

Other therapy related costs

  

ECG

€3.44

 

Hospitalization cost (cost per diem)

 

Government Gazzette, Ministerial Desicion 104494, 26/9/2011

Intensive Care Unit

€200

 

Cardiac Units

€110

 

Other resource use

 

Government Gazzette [16] and local experts’ opinion

On-going HF management costs

€26.05

 
  1. HF: Heart Failure; ECG: electrocardiographic changes; NYHA: New York Heart Association.