Table 2 Mean values of CMA (95% confidence intervals) from ANOVA and ANCOVA analyses
Unadjusted values | Adjusted values | |||||
|---|---|---|---|---|---|---|
N | Mean (%) | 95% CI | n | Mean (%) | 95% CI | |
Simvastatin users with generic substitution | 100,995 | 86.6 | 86.1 – 87.1 | 82,532 | 84.6 | 83.5 – 85.6 |
Simvastatin users with active of generic substitution | 801 | 72.2 | 68.9 – 75.4 | 651 | 71.6 | 66.5 – 76.7 |
Simvastatin users not exposed to generic substitution | 7,010 | 52.8 | 45.8 – 59.8 | 5,590 | 36.7 | 34.8 – 38.7 |
Atorvastatin users | 7,464 | 79.0 | 77.7 – 80.3 | 6,395 | 79.0 | 77.1 – 80.9 |
For those with generic substitution | ||||||
Generic substitution at the first purchase | 64,314 | 83.5 | 82.7-84.2 | 80.4 | 79.4-90.9 | |
Generic substitution later on | 36,681 | 92.2 | 91.8-92.5 | 89.8 | 88.7-90.9 | |