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Table 3 Longitudinal drug data for patients who stayed over 3 days in hospital and in hospice

From: A comparison of drugs and procedures of care in the Italian hospice and hospital settings: the final three days of life for cancer patients

 

Hospital N = 106

Hospice N = 107

P-value

Potentially inappropriate drugs

n.

%

n.

%

 

Supplements

     

Drug not given

59

55.7

97

90.7

 

Drug given continuously

14

13.2

1

0.9

 

Drug stopped in final three days

30

28.3

8

7.5

 

Drug started in final three days

1

0.9

1

0.9

 

Other

2

1.9

-

-

.000

Replacement hormones

     

Drug not given

87

82.1

94

87.9

 

Drug given continuously

12

11.3

1

0.9

 

Drug stopped in final three days

7

6.6

10

9.3

 

Drug started in final three days

-

-

-

-

 

Other

-

-

2

1.9

.007

Antiulcer Drugs

     

Drug not given

25

23.6

37

34.6

 

Drug given continuously

27

25.5

23

21.5

 

Drug stopped in final three days

50

47.2

41

38.3

 

Drug started in final three days

1

0.9

2

1.9

 

Other

3

2.8

4

3.7

.405

Anticoagulents

     

Drug not given

45

42.5

73

68.2

 

Drug given continuously

14

13.2

6

5.6

 

Drug stopped in final three days

40

37.7

21

19.6

 

Drug started in final three days

3

2.8

-

-

 

Other

4

3.8

7

6.5

.001

Antihypertensives

     

Drug not given

71

67.0

97

90.7

 

Drug given continuously

10

9.4

-

-

 

Drug stopped in final three days

19

17.9

9

8.4

 

Drug started in final three days

2

1.9

1

0.9

 

Other

4

3.8

-

-

.000

Antiarryhthmics

     

Drug not given

86

81.1

97

90.7

 

Drug given continuously

8

7.5

3

2.8

 

Drug stopped in final three days

10

9.4

6

5.6

 

Drug started in final three days

1

0.9

1

0.9

 

Other

1

0.9

-

-

.295

Antibiotics

     

Drug not given

41

38.7

90

84.1

 

Drug given continuously

25

23.6

5

4.7

 

Drug stopped in final three days

36

24.5

9

8.4

 

Drug started in final three days

1

0.9

3

2.8

 

Other

3

2.8

-

-

.000

Steroids

     

Drug not given

44

41.5

39

36.4

 

Drug given continuously

25

23.6

22

20.6

 

Drug stopped in final three days

26

24.5

35

32.7

 

Drug started in final three days

8

7.5

3

2.8

 

Other

3

2.8

8

7.5

.174

Vasodilator Drugs

     

Drug not given

93

87.7

102

95.3

 

Drug given continuously

5

4.7

2

1.9

 

Drug stopped in final three days

5

4.7

3

2.8

 

Drug started in final three days

-

-

-

-

 

Other

3

2.8

-

-

.158

Dopamine

     

Drug not given

100

94.3

107

100

 

Drug given continuously

-

-

-

-

 

Drug stopped in final three days

1

0.9

-

-

 

Drug started in final three days

4

3.8

-

-

 

Other

1

0.9

-

-

.101

Potentially appropriate drugs

     

Opioids

     

Drug not given

31

29.2

9

8.4

 

Drug given continuously

30

28.3

70

65.4

 

Drug stopped in final three days

25

23.6

17

15.9

 

Drug started in final three days

14

13.2

8

7.5

 

Other

6

5.7

3

2.8

.001

Midazolam

     

Drug not given

100

94.3

30

28.0

 

Drug given continuously

2

1.9

39

36.4

 

Drug stopped in final three days

-

-

14

13.1

 

Drug started in final three days

4

3.8

19

17.8

 

Other

-

-

5

4.7

.000

Haloperidol

     

Drug not given

94

88.7

38

35.5

 

Drug given continuously

6

5.7

46

43.0

 

Drug stopped in final three days

2

1.9

12

11.2

 

Drug started in final three days

2

1.9

8

7.5

 

Other

2

1.9

3

2.8

.000

Drugs for pulmonary secretions

     

Drug not given

102

96.2

54

50.5

 

Drug given continuously

-0

-

27

25.2

 

Drug stopped in final three days

2

1.9

5

4.7

 

Drug started in final three days

2

1.9

15

14.0

 

Other

-

-

6

5.6

.000

Drugs for Nausea/Vomiting

     

Drug not given

90

84.9

81

75.7

 

Drug given continuously

4

3.8

5

4.7

 

Drug stopped in final three days

8

7.5

17

15.9

 

Drug started in final three days

4

3.8

2

1.9

 

Other

-

-

2

1.9

.166