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Table 1 Formal and surrogate metabolic syndrome characteristics used to define electronic health record metabolic syndrome categories.

From: Identifying primary care patients at risk for future diabetes and cardiovascular disease using electronic health records

Metabolic syndrome criteria Formal NCEP-ATPIII characteristic Surrogate characteristic
Central obesity Waist circumference >102 cm (40") in men, >88 cm (35") in women Body mass index ≥ 29.1 kg/m2 in men, ≥ 27.2 kg/m2 in women;
if height missing, weight ≥ 94.4 kg (201 lbs) in men, ≥ 73.6 kg (162 lbs) in women*
Elevated blood pressure ‡ Average of last two readings ≥ 130 and/or ≥ 85 mmHg or diagnosis of hypertension on problem list and antihypertensive agent on medication list Any of: one blood pressure ≥ 130 and/or ≥ 85 mmHg; on anti-hypertensive medication but no diagnosis on problem list; hypertension from billing codes
Elevated glucose Fasting plasma glucose >5.6 mmol/L (100 mg/dL) Any plasma glucose ≥ 7.8 mmol/L (140 mg/dL)
Elevated triglycerides Fasting plasma level ≥ 1.7 mmol/L (150 mg/dL) Any plasma level ≥ 2.3 mmol/L (200 mg/dL)
Low HDL cholesterol Plasma level <1.0 mmol/L (40 mg/dL) in men, <1.3 mmol/L (50 mg/dL) in women Plasma total cholesterol >5.2 mmol/L (200 mg/dL)
  1. *BMI cut-offs chosen based on report of waist circumference equivalent from the Framingham Offspring Study; weight cut-offs corresponding to the 66th percentile of available weights in the population (percentile based on the percentile of the values for the cut-offs for BMI)
  2. ‡ All patients in our dataset had available data to assess formal criteria of blood pressure, so the surrogate criteria were not used in the present analysis