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Table 1 Summary of results of meta-analysis of warfarin vs. aspirin in patients with atrial fibrillation [11]

From: Values and preferences in oral anticoagulation in patients with atrial fibrillation, physicians' and patients' perspectives: protocol for a two-phase study

  Risk % for 2 years
  Aspirin* Warfarin Difference between aspirin and warfarin
Stroke    
All stroke 7.8 5.0 2.8
   Ischemic stroke 7.4 4 3.4
Fatal ischemic stroke 0.925 0.5 0.425
   Hemorrhagic stroke 0.4 1.0 -0.6
Fatal hemorrhagic stroke 0.19 0.35 -0.16
   Total stroke deaths 1.15 0.85 0.3
All deaths** 10.2 9.4 0.8
Bleeds    
EC bleeding*** 2 3.4 -1.4
Fatal EC bleeding 0.175 0.32 -0.145
  1. *, Data correspond to the aspirin alone arms with exclusion of the aspirin + low-dose warfarin arms of the pooled studies; **, including stroke deaths, cardiovascular deaths, but not extracranial bleeding deaths; ***, EC = extracranial, mostly severe gastrointestinal bleeds requiring admission to hospital, 2 units of blood, or surgery.