Values and preferences in oral anticoagulation in patients with atrial fibrillation, physicians' and patients' perspectives: protocol for a two-phase study

Table 1 Summary of results of meta-analysis of warfarin vs. aspirin in patients with atrial fibrillation [11]

	Risk % for 2 years
	Aspirin*	Warfarin	Difference between aspirin and warfarin
Stroke
All stroke	7.8	5.0	2.8
Ischemic stroke	7.4	4	3.4
Fatal ischemic stroke	0.925	0.5	0.425
Hemorrhagic stroke	0.4	1.0	-0.6
Fatal hemorrhagic stroke	0.19	0.35	-0.16
Total stroke deaths	1.15	0.85	0.3
All deaths**	10.2	9.4	0.8
Bleeds
EC bleeding***	2	3.4	-1.4
Fatal EC bleeding	0.175	0.32	-0.145

*, Data correspond to the aspirin alone arms with exclusion of the aspirin + low-dose warfarin arms of the pooled studies; **, including stroke deaths, cardiovascular deaths, but not extracranial bleeding deaths; ***, EC = extracranial, mostly severe gastrointestinal bleeds requiring admission to hospital, 2 units of blood, or surgery.

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